Fig. 7
From: Mechanisms of different response to ionizing irradiation in isogenic head and neck cancer cell lines
DNA damage signalling and repair gene expression in irradiated isogenic FaDu, FaDu-RR, and 2A3 cells. a Gene expression in 5 Gy-irradiated FaDu-RR cells relative to 5 Gy-irradiated FaDu cells. b Gene expression in 5 Gy-irradiated 2A3 cells relative to 5 Gy-irradiated FaDu cells. Volcano plots show the fold change in gene expression and statistical significance (p-value). The horizontal line shows the statistical significance threshold (p-value < 0.05). Two vertical dashed lines show the threshold of over-expressed (right) and under-expressed genes (left). The solid vertical line shows no change in gene expression. Symbols represent the mean gene expression of each tested gene in 5 Gy-irradiated radioresistant FaDu-RR and radiosensitive 2A3 cells relative to 5 Gy-irradiated parental FaDu cells from three independent experiments