Fig. 5
From: Mechanisms of different response to ionizing irradiation in isogenic head and neck cancer cell lines
DNA damage signalling and repair gene expression in non-irradiated isogenic FaDu, FaDu-RR, and 2A3 cells. a Gene expression in non-irradiated radioresistant FaDu-RR relative to non-irradiated parental FaDu cells; b gene expression in non-irradiated radiosensitive 2A3 cells relative to parental FaDu cells. Volcano plots show the fold change in gene expression and statistical significance (p-value). The horizontal line shows the statistical significance threshold (p-value < 0.05). Two vertical dashed lines show the threshold of over-expressed (right) and under-expressed genes (left), while the solid vertical line shows no change in gene expression. Symbols represent the mean gene expression of each tested gene in FaDu-RR and 2A3 cells relative to parental FaDu cells from three independent experiments