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Table 3 Univariate analysis and multivariate Cox regression for prognosis of 42 SCCE patients

From: Radiotherapy for small cell carcinoma of the esophagus: outcomes and prognostic factors from a retrospective study

Factors

All cohort(n = 42)

LD(n = 25)

P value

(Univariate)

P value

(Multivariate)

HR (95% CI)

P value

(Univariate)

P value

(Multivariate)

HR (95% CI)

Age (< 60 years vs. ≥60 years)

0.280

  

0.989

  

Sex (Male vs. Female)

0.777

  

0.271

  

ECOG PS (≥2 vs. <  2)

0.000

0.001

6.314 (2.027–19.669)

0.048

0.291

2.577 (0.444–14.947)

Lesion length (> 5 cm vs. ≤5 cm)

0.001

0.001

8.593 (2.449–30.156)

0.19

  

Smoking history (Yes vs. No)

0.578

  

0.212

  

Risky diet (Yes vs. No)

0.731

  

0.731

  

Stage (ED vs. LD)

0.002

0.049

2.786 (1.002–7.741)

Treatment (R + C vs. R Only)

0.003

0.088

0.302 (0.076–1.197)

0.028

0.046

0.204 (0.050–0.839)

Technology (3DCRT vs. IMRT)

0.039

0.941

0.948 (0.226–3.974)

0.498

  

RT dose (<56Gy vs. ≥56Gy)

0.024

0.577

1.373 (0.451–4.184)

0.047

0.027

4.212 (1.024–17.335)

  1. Abbreviations: LD: limited-disease, ED: extensive-disease, RT: Radiotherapy, CT: Chemotherapy, HR: Hazard Ratio, CI: Confidence Interval