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Fig. 1 | Radiation Oncology

Fig. 1

From: Mono-institutional phase 2 study of innovative Stereotactic Body RadioTherapy targeting PArtial Tumor HYpoxic (SBRT-PATHY) clonogenic cells in unresectable bulky non-small cell lung cancer: profound non-targeted effects by sparing peri-tumoral immune microenvironment

Fig. 1

a-d Definition of target for SBRT-PATHY: BTV, or “hypoxic“ tumor segment refers to the combined 18F-FDG PET-CT (a, b) and contrast-enhanced CT (d) image findings, derived from the SUV and HU values. This to capture the junctional, contrast-hypo-enhanced (i.e. no significant increase in HU-values after contrast medium injection: c vs. d) and hypometabolic (SUV-value of ≤3 and/or ≤ 30% of SUVmax) tumor regions between the central-necrotic and the remaining peripheral-vascularized and hypermetabolic tumor segments

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