Table 2 Univariate analysis of risk factors for progression free survival (PFS) and overall survival (OS) in 91 patients
Prognostic factors | 2-year PFS (%) [95% CI] | P value | 2-year OS (%) [95% CI] | P value | |
|---|---|---|---|---|---|
Age (yeaars) | ≤38 | 64.1(7.5) | 0.142 | 81.8(6.3) | 0.130 |
>38 | 89.6(5.0) | 92.5(4.3) | |||
Gender | Female | 82.8(6.6) | 0.513 | 88.9(5.3) | 0.686 |
Male | 72.7(6.5) | 86.5(5.2) | |||
KPS | ≥90 | 80.1(4.8) | 0.029 | 90.8(3.6) | 0.008 |
80 | 53.0(15.5) | 59.7(15.9) | |||
Critical organ compression | Yes | 71.1(5.8) | 0.012 | 83.4(4.9) | 0.048 |
No | 95.7(4.3) | 100 | |||
Cranial nerve injury | Yes | 71.4(5.8) | 0.011 | 83.5(4.8) | 0.043 |
No | 95.7(4.3) | 100 | |||
Histology | Chordoma | 73.5(5.5) | 0.132 | 85.9(4.4) | 0.340 |
Chondrosarcoma | 92.9(6.9) | 92.9(6.9) | |||
GTV | ≤60 cc | 84.9(5.0) | 0.004 | 93.9(3.4) | <0.001 |
>60 cc | 59.7(9.5) | 73.2(8.8) | |||
Recurrent disease | Yes | 73.8(6.9) | 0.828 | 82.7(6.0) | 0.260 |
No | 80.4(6.4) | 92.5(4.2) | |||
Re-radiotherapy | Yes | 41.3(15.7) | 0.015 | 50.3(15.5) | <0.001 |
No | 82.8(4.6) | 93.8(3.0) | |||
Surgery times | 1 | 81.1(6.1) | 0.609 | 87.7(5.2) | 0.654 |
≥2 | 71.5(7.3) | 86.3(5.7) | |||
RT | Proton | 100 | 0.69 | 100 | 0.489 |
Proton+carbon | 74.2(8.4) | 84.6(7.1) | |||
Carbon | 75.6(6.3) | 87.3(5.1) |