Table 1 Patient and treatment characteristics (n = 32 patients)
From: Rare entities in head-and-neck cancer: salvage re-irradiation with carbon ions
Patient characteristics | ||
Patients | % | |
Gender | ||
Female | 15 | 46.9 |
Male | 17 | 53.1 |
Age | ||
≥ 60 years | 19 | 59.4 |
< 60 years | 12 | 40.6 |
ECOG status | ||
0 | 16 | 50.0 |
1 | 16 | 50.0 |
Histology | ||
Mucoepidermoid carcinoma | 7 | 21.9 |
Acinar cell carcinoma | 6 | 18.8 |
Esthesioneuroblastoma | 5 | 15.6 |
Lymphoepithelial carcinoma | 4 | 12.5 |
Myoepithelial carcinoma | 3 | 9.4 |
Sinonasal undifferentiated carcinoma | 2 | 6.2 |
Salivary duct carcinoma | 2 | 6.2 |
Other | 3 | 9.4 |
Tumor site | ||
Major salivary gland | 15 | 46.8 |
Nasopharynx | 7 | 21.9 |
Paranasal sinus | 6 | 18.8 |
Other | 4 | 12.5 |
Tumor stage | ||
T1 + T2 | 3 | 9.4 |
T3 + T4 | 24 | 75.0 |
Undetermined | 5 | 15.6 |
Metastasis stage | ||
M0 | 28 | 87.5 |
M1 | 4 | 12.5 |
Treatment characteristics | ||
Salvage surgery | ||
No | 25 | 78.1 |
Yes | 7 | 21.9 |
Re-irradiation | ||
Median | Range | |
Total dose CIR [Gy (RBE)] | 51.0 | 36.0–66.0 |
Cumulative tumor lifetime dose [EQD2] | 128.6 | 105.8–146.5 |
CTV re-irradiation [cubic cm] | 98.3 | 13.3–550.6 |
PTV re-irradiation [cubic cm] | 137.1 | 23.1–714.9 |