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Table 6 Dosimetric comparison between plans used to train CL-1 (clinical plans) and TP-1 (from simple template) models. Errors refer to the standard deviation of the mean. p is the significance value according to the Student t-test

From: RapidPlan knowledge based planning: iterative learning process and model ability to steer planning strategies

Organ

Parameter

Plans for CL-1

Plans for TP-1

p

Difference TP-CL (%)

Brain Stem

D1% (Gy)

29.1 ± 1.7

46.2 ± 1.4

< 0.001

+ 58.8

Spinal Cord

D1% (Gy)

31.7 ± 0.8

36.5 ± 0.9

0.008

+ 15.1

Parotids

Mean (Gy)

25.9 ± 0.7

27.9 ± 0.5

< 0.001

+ 7.7

Oral Cavity

Mean (Gy)

44.1 ± 1.0

40.7 ± 0.8

< 0.001

−7.7

Larynx

Mean (Gy)

38.5 ± 1.7

50.2 ± 1.5

< 0.001

+ 30.4

Thyroid

Mean (Gy)

46.5 ± 1.1

44.5 ± 0.9

0.001

− 4.3

Non-target tissue

Mean (Gy)

7.6 ± 0.4

9.1 ± 0.4

< 0.001

+ 19.7

V40Gy (cm3)

666 ± 23

1031 ± 28

< 0.001

+ 54.8

PTV_boost

D5% (%)

102.6 ± 0.6

103.0 ± 1.2

0.001

 

D95% (%)

95.6 ± 1.0

94.9 ± 2.4

0.009

 

PTV_elective

D5% (%)

104.7 ± 1.2

104.4 ± 1.3

0.100

 

D95% (%)

95.8 ± 1.1

96.9 ± 1.5

< 0.001

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