Comparison of the outcomes of stereotactic body radiotherapy versus surgical treatment for elderly (≥70) patients with early-stage non-small cell lung cancer after propensity score matching

Table 1 Characteristics of the entire patient cohort

Factor	SBRT (N = 99)	Surgery (N = 106)	p-value
Age (years)
Median (range)	78 (70–88)	73 (70–83)	0.001
Gender
Male	77	61	0.001
Female	22	45
Tumor size (cm)
Median (range)	2.2 (1.0–5.0)	2.0 (1.0–5.0)	0.621
T stage
T1	83	86	0.740
T2	16	20
Histology
NSCLC-NOS	18	4	0.001
SCC	32	25
Ade	35	77
probable	14	0
FEV1
Median (range)	1.26 (0.38–2.51)	1.74 (0.78–3.04)	0.001
FEV1/FVC (%)
Median (range)	91 (38–129)	107 (54–126)	0.001
CCI (%)
0	45 (46)	77 (73)	0.001
1–2	48 (48)	25 (24)
≥ 3	6 (6)	4 (2)
KPS
Median (range)	90 (60–100)	90 (80–100)	0.347
Tumor location
RUL	26	29	0.323
RML	18	16
RLL	21	20
LUL	15	26
LLL	19	15
SBRT dose
50Gy/4fx	19		N/A
50Gy/5fx	60
50Gy/10fx	12
60Gy/8fx	5
70Gy/10fx	3
Operation
lobectomy		90	N/A
sublobar resection		16
VATS		84
thoracotomy		22

SBRT stereotactic body radiotherapy, NSCLC non–small cell lung cancer, NOS not otherwise specified, Ade adenocarcinoma, SCC squamous cell carcinoma, FEV1 forced expiratory volume in 1 s, FEV1/FVC% FEV1 to forced vital capacity ratio, CCI Charlson comorbidity index, KPS Karnofsky performance status, fx fractions, RUL right upper lobe, RML right middle lobe, RLL right lower lobe, LUL left upper lobe, LLL left lower lobe, VATS video-assisted thoracic surgery

ISSN: 1748-717X