Skip to main content

Table 3 Late toxicity in the second cohort from the assessment at the time of analysis

From: Conventional versus hypofractionated postmastectomy radiotherapy: a report on long-term outcomes and late toxicity

Toxicity

CF-PMRT

n (%)

N = 457

HF-PMRT

n (%)

N = 480

p-value

Skina

  

< 0.001

 Grade 0

197 (43)

340 (71)

 

 Grade 1

255 (56)

122 (25)

 

 Grade 2

5 (1)

9 (2)

 

 Grade 3

0 (0)

9 (2)

 

Subcutaneous tissuea

  

< 0.001

 Grade 0

261 (57)

370 (77)

 

 Grade 1

185 (41)

75 (16)

 

 Grade 2

11 (2)

35 (7)

 

Lung (Clinical)a

  

< 0.001

 Grade 0

389 (85)

239 (50)

 

 Grade 1

62 (14)

240 (50)

 

 Grade 2

6 (1)

1 (< 1)

 

Lung (Imaging)a

  

< 0.001

 Grade 0

184 (40)

249 (52)

 

 Grade 1

199 (44)

187 (39)

 

 Grade 2

24 (5)

7 (1)

 

 Grade 3

50 (11)

37 (8)

 

Hearta

  

0.840

 Grade 0

453 (99)

477 (99)

 

 Grade 1

0 (0)

0 (0)

 

 Grade 2

1 (< 1)

0 (0)

 

 Grade 3

3 (< 1)

3 (< 1)

 

Lymphedemab

  

0.905

 Stage 0

442 (97)

467 (97)

 

 Stage 1

11 (2)

9 (2)

 

 Stage 2

4 (1)

4 (1)

 

Brachial Plexopathyc

  

< 0.001

 Grade 0

421 (92)

469 (98)

 

 Grade 1

36 (8)

11 (2)

 
  1. CF-PMRT Conventional fractionated post mastectomy radiotherapy, HF-PMRT Hypofractionated post mastectomy radiotherapy, N number
  2. aRTOG/EORTC Late Radiation Morbidity Scoring Schema [11]
  3. bISL [12]
  4. cModified LENT SOMA scales [13]