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Table 2 Risk factor analysis for pre-PCI brain metastasis

From: Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer

Covariates Univariate Multivariate
RR (95% CI) P RR (95% CI) P
Age at diagnosis 0.976 (0.924–1.032) 0.400   
Gender 0.510 (0.107–2.437) 0.399   
Smoking 3.781 (0.822–17.400) 0.088 4.376 (0.895–21.394) 0.068
T stage (1–2 vs 3–4) 1.383 (0.546–3.502) 0.494 1.099 (0.411–2.941) 0.851
N stage (0–2 vs 3) 1.458 (0.499–4.259) 0.490 1.389 (0.456–4.235) 0.564
CRT-D (months) 1.340 (0.981–1.831) 0.066 1.406 (1.007–1.964) 0.045*
  1. Abbreviation: PCI Prophylactic cranial irradiation, RR Risk ratio, CI Confidence interval, CRT-D Chemoradiotherapy duration. Age and CRT-D as continuous variables. Binary logistic regression was employed for analysis. (*) statistically significant