Table 3 Univariable analysis of factors influencing overall survival after primary resection of atypical meningioma. P-values ≤0.05 were defined as statistically significant (*). Tumor localization in multivariable analysis was performed according to the CLASS algorithm (and not as “skullbase vs non-skullbase”) because this information is already included in the CLASS algorithm
From: Adjuvant radiotherapy improves progression-free survival in intracranial atypical meningioma
Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
p | HR | 95% CI | p | HR | 95% CI | |
Adjuvant radiotherapy (Intervention vs. control) | 0.661 | 0.709 | 0.152–3.301 | 0.309 | 0.238 | 0.015–3.797 |
Sex (Male vs. female) | 0.49 | 0.654 | 0.196–2.185 | 0.954 | 1.052 | 0.191–5.781 |
Simpson resection grade14 (Grade IV/V vs. Grade I/II/III) | 0.575 | 1.172 | 0.674–2.037 | 0.295 | 1.452 | 0.722–2.919 |
Patient age at first diagnosis (> median vs. ≤ median) | 0.048* | 3.978 | 1.012–15.641 | 0.095 | 5.278 | 0.748–37.243 |
Pretherapeutic tumor volume (> median vs. ≤ median) | 0.143 | 3.28 | 0.668–16.104 | 0.678 | 1.439 | 0.258–8.04 |
Intracranial tumor localization (CLASS moderate/high risk vs. low risk) | 0.711 | 0.893 | 0.492–1.621 | 0.463 | 0.691 | 0.258–1.852 |
Intracranial tumor localization (non-skull base vs. skull base) | 0.723 | 1.002 | 0.990–1.015 | |||