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Table 1 Patient characteristics. SRS = stereotactic radiosurgery

From: Adjuvant radiotherapy improves progression-free survival in intracranial atypical meningioma

Characteristics

Total

n = 99

Intervention

n = 19

Control

n = 80

p-value

Median (Min/Max)

Median (Min/Max)

Median (Min/Max)

Patient age at first diagnosis (years)

59

59

59

0.49

(22/84)

(26/75)

(22/84)

Pretherapeutic tumor volume (cm3)

29.7

47.1

26.1

0.16

(0.8/153.9)

(12.6/90.2)

(0.8/153.9)

 

n (%)

n (%)

n (%)

 

Sex

 Male

42 (42.4)

8 (42.1)

34 (42.5)

0.98

 Female

57 (57.6)

11 (57.9)

46 (57.5)

Tumor location

 Convexity

36 (36.4)

7 (36.8)

29 (36.3)

0.91

 Olfactory groove / Planum sphenoidale

4 (4.0)

0 (0.0)

4 (5)

 Lateral sphenoid wing / Temporal bone

6 (6.1)

2 (10.5)

4 (5)

 Parasagittal / Falx

23 (23.2)

4 (21.1)

19 (23.8)

 Cerebellopontine angle

3 (3.0)

1 (5.3)

2 (2.5)

 Petroclival

1 (1.0)

0 (0)

1 (1.3)

 Medial sphenoid wing / Clinoid / Orbital

17 (17.2)

4 (21.1)

13 (16.3)

 Tuberculum sellae

3 (3.0)

0 (0)

3 (3.8)

 Cavernous sinus

0 (0.0)

0 (0)

0 (0)

 Tentorial

6 (6.1)

1 (5.3)

5 (6.3)

 Foramen magnum

0 (0.0)

0 (0)

0 (0)

 Optic nerve sheath

0 (0.0)

0 (0)

0 (0)

Simpson grade

 1

24 (24.2)

5 (26.3)

19 (23.8)

0.39

 2

35 (35.4)

4 (21.1)

31 (38.8)

 3

1 (1.0)

0 (0)

1 (1.3)

 4

11 (11.1)

4 (21.1)

7 (8.8)

 5

1 (1.0)

1 (5)

0 (0)

 Not documented

27 (27.3)

5 (26.3)

22 (27.5)

Salvage therapies

 No recurrence

58 (58.6)

16 (84.2)

42 (52.5)

 

 Resection

3 (3.0)

0 (0.0)

3 (3.8)

 Radiotherapy

19 (19.2)

2 (10.5)

17 (21.3)

 Resection and Radiotherapy

19 (19.2)

1 (5.3)

18 (22.5)

Fractionation scheme

 Not irradiated

80 (80.8)

0 (0)

80 (100)

 

 Normofractionation (1.8–2.2 Gy)

17 (17.1)

17 (89.5)

0 (0)

 Hypofractionation (> 2.2–5 Gy)

1 (1)

1 (5.3)

0 (0)

 SRS (> 5 Gy)

1 (1)

1 (5.3)

0 (0)