Group 1 (n = 19) | Group 2 (n = 44) | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Before RT | After RT | 3 year | Before RT | After RT | 3 year | |||||||||||||
n | Md | (IQR) | Md | (IQR) | Md | (IQR) | p1 | p2 | n | Md | (IQR) | Md | (IQR) | Md | (IQR) | p1 | p2 | |
LV measurements | ||||||||||||||||||
LVEDD (mm) | 19 | 46.0 | (44.0–48.0) | 45.0 | (44.0–50.0) | 46.0 | (42.0–50.0) | 0.513 | 0.446 | 44 | 46.0 | (44.0–47.0) | 46.0 | (43.3–47.0) | 45.0 | (43.0–47.0) | 0.904 | 0.654 |
LVESD (mm) | 19 | 31.0 | (29.0–34.0) | 32.0 | (28.0–34.0) | 31.0 | (29.0–35.0) | 0.854 | 0.954 | 44 | 31.0 | (29.0–32.8) | 30.5 | (29.0–31.8) | 30.0 | (29.0–32.0) | 0.781 | 0.896 |
IVS (mm) | 19 | 10.0 | (9.0–11.0) | 11.0 | (10.0–12.0) | 11.0 | (10.0–11.0) | 0.036 | 0.157 | 44 | 10.0 | (9.0–11.0) | 10.0 | (9.0–11.0) | 10.0 | (9.0–11.0) | 0.378 | 0.775 |
PW (mm) | 19 | 10.0 | (9.0–11.0) | 11.0 | (10.0–12.0) | 9.0 | (10.0–11.0) | 0.030 | 0.434 | 44 | 10.0 | (9.0–11.0) | 10.0 | (9.3–11.0) | 9.0 | (8.3–10.0) | 0.144 | 0.028 |
LV systolic function | ||||||||||||||||||
LV EF (%) | 19 | 62.0 | (56.0–65.0 | 61.0 | (58.0–65.0) | 60.0 | (57.0–63.0) | 0.886 | 0.144 | 44 | 62.0 | (60.0–65.0 | 63 | (59.3–65.0) | 61.5 | (57.0–63.0) | 1.000 | 0.092 |
GLS (%) | 17 | ─17.0 | (─20.5-─16.0) | ─17.0 | (─19.5-─15.5) | ─16.0 | (─18.5-─14.0) | 0.373 | 0.006 | 44 | ─18.0 | (─19.8-─15.0) | ─17.0 | (─20.0-─15.0) | ─18.0 | (─20.0-─16.0) | 0.159 | 0.762 |
LV diastolic function | ||||||||||||||||||
Mitral inflow E (cm/s) | 19 | 73.5 | (66.2–81.9) | 66.1 | (57.2–79.0) | 66.2 | (61.7–78.4) | 0.113 | 0.106 | 44 | 75.4 | (63.8–87.3) | 72.4 | (60.3–80.0) | 71.4 | (62.0–89.0) | 0.139 | 0.242 |
Ee’ ratio | 19 | 8.3 | (6.8–10.2) | 7.8 | (7.1–11.1) | 8.7 | (7.1–10.2) | 0.701 | 0.347 | 44 | 9.5 | (7.7–11.4) | 9.3 | (7.1–10.2) | 8.9 | (7.7–11.0) | 0.076 | 0.337 |
RV function | ||||||||||||||||||
TAPSE (mm) | 17 | 24.0 | (21.0–28.0) | 21.0 | (18.5–24.5) | 22.0 | (20.5–27.5) | 0.021 | 0.363 | 42 | 24.5 | (20.8–27.3) | 22.0 | (19.0–26.0) | 24.0 | (20.0–26.0) | 0.001 | 0.119 |
TR gradient (mmHg) | 12 | 21.0 | (18.3–26.0) | 20.5 | (17.3–24.0) | 23.5 | (19.3–28.5) | 0.351 | 0.381 | 35 | 21.0 | (17.0–25.0) | 22.0 | (19.0–24.0) | 24.0 | (20.0–29.0 | 0.811 | < 0.001 |
Tissue characterization | ||||||||||||||||||
scIBS (dB) | 17 | 15.5 | (12.5–21.3) | 19.5 | (13.7–25.1) | 23.3 | (20.1–25.8) | 0.031 | < 0.001 | 44 | 17.6 | (14.1–22.1) | 19.6 | (16.3–24.2) | 20.3 | (18.8–22.8) | 0.007 | 0.002 |
rcIBS (dB) | 17 | 18.7 | (14.8–21.8) | 22.9 | (20.1–25.9) | 23.5 | (19.1–27.0) | 0.011 | 0.013 | 44 | 21.1 | (17.1–24.6) | 23.0 | (18.0–26.9) | 24.1 | (20.3–27.0) | 0.208 | 0.021 |
pcIBS (dB) | 17 | 10.3 | (7.6–11.9) | 9.2 | (8.2–12.1) | 9.4 | (6.5–13.1) | 0.579 | 0.854 | 43 | 9.8 | (6.8–13.9) | 10.3 | (8.3–12.5) | 10.5 | (6.8–13.4) | 0.888 | 0.959 |