The impact of the nodal status on the overall survival of non-surgical patients with esophageal squamous cell carcinoma

Table 4 Multivariate Cox regression analysis of the prognostic factors for OS in patients with ESCC

Prognostic Factor	HazardRatio	95% CI	P
Age(<60 vs ≥60)	0.890	0.637–1.243	0.495
Sex (Male vs Female)	0.722	0.503–1.304	0.076
Primary tumor location (baseline, Upper)			0.010
Middle	1.292	0.948–1.761	0.105
Lower	1.790	1.229–2.607	0.002
T category (baseline, T2)			0.013
T3	1.171	0.795–1.724	0.425
T4	1.827	1.162–2.872	0.009
No. of LNs (N0, < 3 vs ≥3)	1.667	1.177–2.361	0.004
Extent of LNs (baseline, N0)			0.044
1 region	1.365	0.834–2.087	0.125
2 regions	1.575	0.989–2.508	0.056
3 regions	2.475	1.178–5.159	0.016
Size of LNs (N0, ≤2 vs > 2 cm)	0.812	0.527–1.252	0.347
Treatment (CRT vs RT alone)	0.569	0.425–0.762	0.001

LNs Lymph nodes, CI Confidence interval, CRT Chemoradiotherapy, RT Radiotherapy

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