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Table 2 Dose parameters for organs at risk, i.e. average dose (in Gy) to heart, LADCA, and left lung for 20 patients with left-sided breast cancer comparing t-IMRT and t-VMAT, both in DIBH-technique

From: Left breast irradiation with tangential intensity modulated radiotherapy (t-IMRT) versus tangential volumetric modulated arc therapy (t-VMAT): trade-offs between secondary cancer induction risk and optimal target coverage

Heart dose

DIBH-t-IMRT

DIBH-t-VMAT

Difference

p-value

Dmean

2.96 ± 0.61

4.03 ± 0.74

- 1.07 (− 26%)

0.002

D25%

3.84 ± 0.69

4.81 ± 0.81

- 0.97 (−20%)

0.002

D45%

2.68 ± 0.69

3.81 0.63

- 1.13 (−29%)

0.003

LADCA dose

Dmax

12.28 ± 3.49

15.45 ± 5.6

- 3.17 (−20%)

0.003

Dmean

5.80 ± 0.68

7.31 ± 0.97

- 1.51 (−20%)

0.03

D25%

6.58 ± 0.68

8.48 ± 1.18

−1.9 (−22%)

0.01

Left Lung

Dmean

10.42 ± 0.71

9.89 ± 1.03

+ 0,53 (+ 5%)

0.006