Sequential short-course radiation therapy and chemotherapy in the neoadjuvant treatment of rectal adenocarcinoma

Radiation Oncology

Table 2 Treatment results

Patient	Clinical stage	Post-treatment MRI TRG	Post-treatment endoscopy response	Time to surgery (weeks)	Pathologic stage	Radial Margin	Pathologic TRG	NAR
1	T2 N1	3	No post-treatment endoscopy	18.1	T3 N1	Negative	Not assessed	41.6
2	T2 N1	–	Complete	–	–	–	–	N/A
3	T2 N2	3	No post-treatment endoscopy	12.9	T2 N0	Negative	1	15
4	T2 N2	1	Complete	–	–	–	–	N/A
5	T2 N2	3	Not complete	25.7	TisN0	Negative	0*	0
6	T3 N0	2	No post-treatment endoscopy	17.3	T0 N0	Negative	0	0.9
7	T3 N0	2	Complete	–	–	–	–	N/A
8	T3 N1	–	No post-treatment endoscopy	12.3	T0 N0	Negative	0	0.9
9	T3 N1	2	Not complete	13.0	T3 N0	Negative	1	15
10	T3 N1	2	Complete	16.9	T3 N1	Negative	1	30.1
11	T3 N1	2	Not complete	13.6	T0 N0	Negative	0	0.9
12	T3 N2	2	Not complete	23.4	T3 N2	Positive	3	50.4
13	T3 N2	3	Not complete	17.9	T1 N0	Negative	2	3.7
14	T3 N2	3	Not complete	17.3	T1 N0	Negative	3	3.7
15	T3 N2	1	Not complete	13.6	T0 N0	Negative	0	0.9
16	T3 N2	3	No post-treatment endoscopy	14.1	T2 N1	Negative	2	20.4
17	T3 N2	1	Complete	–	–	–	–	N/A
18	T3 N2	2	No post-treatment endoscopy	13.9	T0 N0	Negative	0	0.9
19	T3 N2	2	Complete	24.3	T0 N0	Negative	0	0.9
20	T3 N2	3	Complete	18	T3 N1	Negative	2	30.1
21	T3 N2	3	Not complete	13.6	T3 N1	Negative	2	20.4
22	T4bN0	1	Complete	–	–	–	–	N/A
23	T4aN1	–	No post-treatment endoscopy	13	T0 N0	Negative	0	0
24	T4aN2	3	Not complete	13.9	T3 N1	Positive	2	20.4
25	T4aN2	3	Not complete	13.1	T3 N1	Negative	2	20.4
26	T4bN2	3	Complete	–	–	–	–	N/A

Abbreviations: TRG treatment response grade, CCR clinical complete response, NAR neoadjuvant response score
Note: Patients without pathology assessment were those followed with watch-and-wait approach. Pathologic tumor regression of 0 represents pathologic complete response. *The patient with pTis disease is assigned a score of 0

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