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Fig. 4 | Radiation Oncology

Fig. 4

From: Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity

Fig. 4

After irradiation (8 Gy), NOX4 mRNA level is significantly increased in PBMCs of patients with grade ≥ 2 bf+. a NOX4 mRNA expression (qRT-PCR analysis) in patients with grade < 2 bf + (n = 13) and with grade ≥ 2 bf + (n = 7) before (circles) and at 24 h after 8 Gy-irradiation (squares). b NOX4 protein expression (western blotting) in patients with grade < 2 bf + (n = 13) and grade ≥ 2 bf + (n = 7) before (circles) and at 24 h after 8 Gy-irradiation (squares) (two-way ANOVA with Bonferroni post-tests). NS: Not Significant; *p < 0.05, by paired t-test. Data are the mean ± SEM

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