Impact of adaptive intensity-modulated radiotherapy on the neutrophil-to-lymphocyte ratio in patients with nasopharyngeal carcinoma

Table 4 Univariate analysis of the ΔNLR, ΔCLC, and ΔCPC

Characteristics	ΔNLR				ΔCLC				ΔCPC
Characteristics	Regression coefficient	SD	P	Pearson coefficient	Regression coefficient	SD	P	Pearson coefficient	Regression coefficient	SD	P	Pearson coefficient
Age (years)	0.003	0.009	0.757	0.310	0.002	0.025	0.942	0.007	−0.003	0.003	0.333	−0.098
Gender	−0.225	0.203	0.270	−0.111	−0.782	0.564	0.169	−0.139	−0.024	0.061	0.702	− 0.039
History of smoking	0.202	0.193	0.297	0.105	−0.067	0.543	0.902	−0.013	− 0.067	0.058	0.253	−0.115
History of drinking	0.221	0.248	0.375	0.090	0.375	0.696	0.591	0.054	0.050	0.075	0.503	0.068
Family history	−0.354	0.247	0.155	−0.143	0.189	0.697	0.787	0.027	−0.031	0.075	0.679	−0.042
T stage	−0.243	0.129	0.064	−0.186	0.593	0.363	0.105	0.163	0.017	0.040	0.662	0.044
N stage	−0.015	0.119	0.902	−0.013	−0.208	0.333	0.535	−0.063	0.028	0.036	0.435	0.079
Clinical stage	−0.719	0.205	0.001^*	−0.334	1.023	0.600	0.091	0.170	−0.015	0.066	0.816	−0.024
ART	−0.721	0.177	< 0.001^*	−0.380	2.150	0.490	< 0.001^*	0.406	0.121	0.057	0.035^*	0.211
Acute radiation injury classification
Parotid glands	0.426	0.282	0.133	0.151	−0.594	0.791	0.456	−0.075	− 0.077	0.086	0.370	−0.091
Skin	0.536	0.136	< 0.001^*	0.370	−0.785	0.401	0.053	−0.194	−0.046	0.044	0.293	−0.106
Oral	0.110	0.104	0.296	0.106	0.331	0.291	0.258	0.114	−0.001	0.032	0.978	−0.003

Abbreviations: ART adaptive radiotherapy, NLR neutrophil-to-lymphocyte ratio, CLC circulating lymphocyte count, CPC circulating platelet count
^*P ≤ 0.05

ISSN: 1748-717X