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Table 1 Plan optimization objectives

From: Radiation treatment planning with embedded dose escalation

Optimization Approach Structure Metric Value (Gy) Weight
All (Max. OAR Dose Objective) OAR Max. Dose 24.5 5
All (Gradient Objective) OAR Max. D40%* 17.5 5
All (Gradient Objective) External Contour Minus Target & OAR Max. D10%** 7.5 5
Baseline Target Min. Dose 25 10
DVH Target Min. Dose 25 10
DVH Target Min. D10%** 80–100 0.1–10
Sub-Structure Target Min. Dose 25 10
Sub-Structure Sub-Structure Min. Dose 50–100 1–10
gEUD (a = −1) Target Min. gEUD (a = − 1) 100 10
gEUD (a = −5) Target Min. gEUD (a = − 5) 75 10
gEUD (a = − 15) Target Min. gEUD (a = − 15) 60–75 10
  1. *dose to 40% of the structure, **dose to 10% of the structure