Table 1 Plan optimization objectives
From: Radiation treatment planning with embedded dose escalation
Optimization Approach | Structure | Metric | Value (Gy) | Weight |
|---|---|---|---|---|
All (Max. OAR Dose Objective) | OAR | Max. Dose | 24.5 | 5 |
All (Gradient Objective) | OAR | Max. D40%* | 17.5 | 5 |
All (Gradient Objective) | External Contour Minus Target & OAR | Max. D10%** | 7.5 | 5 |
Baseline | Target | Min. Dose | 25 | 10 |
DVH | Target | Min. Dose | 25 | 10 |
DVH | Target | Min. D10%** | 80–100 | 0.1–10 |
Sub-Structure | Target | Min. Dose | 25 | 10 |
Sub-Structure | Sub-Structure | Min. Dose | 50–100 | 1–10 |
gEUD (a = −1) | Target | Min. gEUD (a = − 1) | 100 | 10 |
gEUD (a = −5) | Target | Min. gEUD (a = − 5) | 75 | 10 |
gEUD (a = − 15) | Target | Min. gEUD (a = − 15) | 60–75 | 10 |