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Table 4 Comparison of acute GI and GU toxicity rates 1 month following 5-fraction prostate SBRT. A perirectal spacer was not used in the earlier series shown below

From: Stereotactic body radiotherapy with periprostatic hydrogel spacer for localized prostate cancer: toxicity profile and early oncologic outcomes

Study   Current series Madsen
(IJROBP 2006)
Loblaw
(Rad Oncol 2013)
Katz
(BMC Urol 2010)
Chen
(BMC Rad Onc 2013)
Park
(BMC Rad Onc 2018)
McBride
(Cancer 2011)
Dose (Gy)   36.25 33.5 35 35-36.25 35-36.25 35-36.25 36.25-37.5
Grade (GI) n 50 39 84 304 100 88 42
 0   88% 61% 23% 21% 60% 58% 62%
 1   8% 26% 67% 74% 35% 36% 31%
 2   4% 13% 10% 5% 5% 6% 7%
Grade (GU)
 0   44% 49% 9% 20% 29% 42% 21%
 1   26% 28% 71% 75% 36% 49% 60%
 2   30% 21% 19% 5% 35% 9% 19%
 3   0% 2% 1% 0% 0% 0% 0%