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Table 2 Characteristics of the developed small animal irradiators [3]

From: Preclinical dosimetry: exploring the use of small animal phantoms

Model

Source

Imaging

Positioning

Additional

SARRP (Xstrahl Ltd)

X-ray, 5–225 keV

Amorphous Si flat panel detector for dual imaging system (CT) and planar X-ray

Robotically-controlled stage, 35 cm SSD, 4 degrees of freedom.

Allows continuous radiation delivery either from rotating gantry or platform.

2 collimation systems: 1 for precision with smaller, conformal inserts, another for higher throughput with larger square field sizes.

X-Rad 225Cx (Precision X-Ray Inc)

X-ray, 5–225 keV

Amorphous Si flat panel for single image or cone beam CT.

3D computer controlled stage with automated corrections

Selection of beam collimators providing 0.2 mm accuracy

Washington University

Iridium 192 (brachytherapy)

N/A (fiducial markers)

Computer controlled stage, 4 gantry angles

Tungsten collimators 5-15 mm

Stanford University

X-ray, 70–120 keV (microCT scanner)

Designed for small animal imaging so 0.1 mm spatial resolution

Arc or fixed field

Brass iris collimators (0.1-6 cm field sizes

University of Texas Southwestern

X-ray 5–320 keV

Fixed panel

3D precision stage, cylinder for immobilisation

Cylindrical collimators 1-10 mm

  1. Key: SARRP small animal radiation research platform, keV kiloelectron volts, CT computed tomography, SSD source to surface distance