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Table 3 GLM summary including odds ratios (OR) and 95% confidence interval (CI) for the prediction of xerostomia

From: Predicting acute radiation induced xerostomia in head and neck Cancer using MR and CT Radiomics of parotid and submandibular glands

 

DVH Model

CT Model

MR Model

Clinical + DVH + CT + MR Model

β

OR

(95% CI)

β

OR

(95% CI)

β

OR

(95% CI)

β

OR

(95% CI)

Intercept

−2.58

−9.21

 

−0.31

 

−6.54

 

Age

−0.69

0.50 (0.47–0.54)

Gender

1.09

2.97 (1.93–4.01)

Tumor Volume

0.45

1.56 (1.56–1.58)

cPG D40

1.51

4.57 (4.56–4.58)

1.03

2.79 (2.78–2.79)

cSG D60

0.60

1.81 (1.80–1.82)

0.63

1.86 (1.86–1.88)

CT cSG wavelet LLL GLSZM Gray Level Non Uniformity Normalized

1.00

2.73 (−11.3–16.7)

0.83

2.29 (−14.4–19.0)

CT iPG original GLSZM Low Gray Level Zone Emphasis

−0.64

0.53 (−9.0–10.1)

− 0.61

0.55 (−10.4–11.5)

CT iSG wavelet HLL GLCM Inverse Variance

0.57

1.77 (−17.4–20.9)

0.36

1.44 (−21.9–24.8)

CT cPG wavelet LHL Total Energy

0.42

1.53 (1.52–1.54)

0.31

1.36 (1.35–1.37)

CT iSG wavelet HLL GLRLM Long Run High Gray Level Emphasis

−0.65

0.52 (0.51–0.53)

−0.69

0.50 (0.49–0.51)

CT iPG original first order 10 Percentile

−0.69

0.50 (0.49–0.51)

−0.38

0.69 (0.68–0.70)

CT cPG wavelet LHL GLRLM Long Run High Gray Level Emphasis

0.43

1.54 (1.53–1.55)

0.49

1.63 (1.62–1.64)

MR cPG shape Least Axis Length

0.98

2.66 (2.59–2.73)

0.84

2.32 (2.23–2.42)

MR iSG wavelet LHH GLSZM Gray Level Non Uniformity Normalized

−0.65

0.52 (−26.2–27.2)

−0.92

0.40 (−33.8–34.6)

MR iSG wavelet LHH GLSZM Small Area High Gray Level Emphasis

1.17

3.22 (3.20–3.23)

1.28

3.59 (3.57–3.61)

MR iPG wavelet LHL GLSZM Small Area High Gray Level Emphasis

−0.69

0.50 (0.48–0.52)

−0.72

0.49 (0.47–0.51)

MR iSG wavelet LLH GLSZM Size Zone Non Uniformity Normalized

−0.36

0.70 (−9.75–11.2)

− 0.43

0.65 (−12.3–13.6)

  1. iPG ipsilateral parotid gland, cPG contralateral parotid gland, iSG ipsilateral submandibular gland, cSG contralateral submandibular gland, GLCM gray level co-occurrence matrix, GLSZM gray level size zone matrix, GLRLM gray level run length matrix; bold indicates significant values (p < .05)