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Table 4 Multivariate logistic regression models for the risk of perineal wound complications

From: Excluding the ischiorectal fossa irradiation during neoadjuvant chemoradiotherapy with intensity-modulated radiotherapy followed by abdominoperineal resection decreases perineal complications in patients with lower rectal cancer

Variable

n (%)

OR(95%CI)

p

Absent (n = 148)

Present (n = 66)

Preoperative haemoglobin level (g/dl)

 ≥ 11

137(93.8)

53(82.8)

Ref

 

 < 11

9(6.2)

11(17.2)

3.776 (1.380–10.355)

0.010

Operation duration (min)

 ≤ 180

84(56.8)

23(34.8)

Ref

 

 > 180

64(43.2)

43(65.2)

2.486 (1.287–4.804)

0.007

Hypertension

 No

117(79.1)

43(65.2)

Ref

 

 Yes

31(20.9)

23(34.8)

1.962 (0.958–4.019)

0.065

Blood transfusion

 No

137(92.6)

54(81.8)

Ref

 

 Yes

11(7.4)

12(18.2)

1.702 (0.577–5.022)

0.336

Time interval between NCRT and APR (weeks)

 ≤ 8

76(51.4)

22(33.3)

Ref

 

 > 8

72(48.6)

44(66.7)

2.400 (1.237–4.656)

0.010

Irradiation of IRF

 No

94(63.5)

30(45.5)

Ref

 

 Yes

54(36.5)

36(54.5)

2.892 (1.490–5.615)

0.002

  1. Abbreviations: NCRT Neoadjuvant chemoradiotherapy, APR Abdominoperineal resection, IRF Ischiorectal fossa, Ref Reference