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Table 3 Ratio and quartile analysis of Gaussian simulations

From: Statistical evaluation of worst-case robust optimization intensity-modulated proton therapy plans using an exhaustive sampling approach

 

Robust IMPT

Mean (SD)

Nominal IMPT

Mean (SD)

P b

CTV1 D95%

 Ratioa

96.96% (6.49%)

89.37% (21.25%)

0.043*

 Median (Gy)

69.92 (0.35)

69.24 (0.53)

0.018*

 Interquartile range (Gy)

1.02 (0.33)

1.34 (0.45)

0.018*

CTV2 D95%

 Ratioa

96.11% (8.57%)

91.29% (15.70%)

0.027*

 Median (Gy)

63.60 (1.49)

62.75 (1.72)

0.018*

 Interquartile range (Gy)

1.49 (0.50)

1.64 (0.61)

0.237

CTV3 D95%

 Ratioa

84.55% (14.64%)

72.94% (18.07%)

0.028*

 Median (Gy)

55.10 (1.61)

54.43 (1.79)

0.028*

 Interquartile range (Gy)

2.20 (1.23)

2.51 (1.31)

0.499

  1. Abbreviations: CTV clinical target volume, Dx dose delivered to x% of the volume
  2. *P values < 0.05 were considered statistically significant
  3. aRatio above 95% of the prescribed dose
  4. bComparison of the selective robust optimization IMPT plan and the nominal IMPT plan
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Radiation Oncology

ISSN: 1748-717X

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