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Table 1 Summary of doses to targets and OARs

From: Statistical evaluation of worst-case robust optimization intensity-modulated proton therapy plans using an exhaustive sampling approach

Parameter

Robust optimization IMPT

Mean (SD)

Nominal IMPT

Mean (SD)

P a

CTV1, D98% (Gy)

70.00 (0.00)

70.00 (0.00)

1.000

CTV2, D98% (Gy)

64.66 (1.27)

64.46 (1.57)

0.735

CTV3, D98% (Gy)

57.47 (0.72)

57.53 (1.05)

0.866

Spinal cord, D1% (Gy)

42.86 (2.88)

40.26 (3.63)

0.028*

Brain stem, D1% (Gy)

45.36 (8.82)

43.82 (9.41)

0.028*

Left parotid, Dmean (Gy)

37.13 (3.98)

36.00 (5.00)

0.398

Right parotid, Dmean (Gy)

37.46 (6.60)

36.72 (5.96)

0.310

  1. Abbreviations: CTV clinical target volume, Dx% dose delivered to x% of the volume, Dmax the maximum dose delivered to the structure, Dmean the average dose delivered to the structure, OARs organs at risk
  2. *P values < 0.05 were considered statistically significant
  3. aComparison of the selective robust optimization IMPT plan and the nominal IMPT plan