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Table 2 Univariate and multivariate models for ipsilateral breast tumor recurrence rate by patient and tumor characteristics

From: The impact of age on the risk of ipsilateral breast tumor recurrence after breast-conserving therapy in breast cancer patients with a > 5 mm margin treated without boost irradiation

Factor

All patients

n = 419

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Age in years

 ≤ 40 vs. ≥41

4.36

1.67–11.39

0.003

   

 ≤ 50 vs. ≥51

2.97

1.19–7.42

0.02

2.73

1.01–7.40

0.047

Pathological T stage

 0, Tis, 1 vs. 2–4

2.19

0.72–6.64

0.17

2.69

0.88–8.22

0.08

Histology

 IDC vs. others

0.93

0.23–3.84

0.92

   

Histological grade

 1 vs. 2

0.72

0.25–2.13

0.56

   

 1 vs. 3

0.52

0.18–1.51

0.23

   

Number of positive nodes

 0 vs. 1–3

0.96

0.52–1.79

0.91

   

 0 vs. ≥4

1.99

0.25–15.85

0.52

   

Hormonal receptor status

 Negative vs. positive

1.09

0.67–1.77

0.74

   

Chemotherapy

 No vs. yes

0.77

0.50–1.19

0.24

0.79

0.49–1.27

0.33

Endocrine therapy

 No vs. yes

0.71

0.24–2.12

0.54

   
  1. Abbreviations: IDC Invasive ductal carcinoma, ILC Invasive lobular carcinoma