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Table 4 Dosimetric comparison for BM, OC and LS

From: Optimal dose limitation strategy for bone marrow sparing in intensity-modulated radiotherapy of cervical cancer

Parameters

IMRT (N)

IMRT (BM)

IMRT (OC)

IMRT (OC + LS)

BM

 Dmean (Gy)

37.57 ± 1.11

32.14 ± 0.25*

32.07 ± 0.61*

29.40 ± 0.52*†

 V10 (%)

97.62 ± 1.98

95.46 ± 2.04*

92.72 ± 2.51*†

92.74 ± 2.31*†

 V20 (%)

88.38 ± 2.87

76.88 ± 1.99*

70.58 ± 2.00*†

65.67 ± 1.44*†

 V30 (%)

72.17 ± 3.67

53.70 ± 1.54*

55.41 ± 2.20*

45.25 ± 1.50*†

 V40 (%)

50.03 ± 4.07

33.47 ± 1.70*

38.64 ± 2.83*†

29.63 ± 1.90*†

 V50 (%)

20.29 ± 2.42

15.79 ± 1.64*

17.11 ± 1.83*

14.77 ± 1.47*

OC

 Dmean (Gy)

33.46 ± 1.46

28.27 ± 0.93*

25.42 ± 0.46*†

25.78 ± 0.59*†

 V10 (%)

96.21 ± 3.15

92.94 ± 3.05*

88.47 ± 3.67*†

89.06 ± 3.31*†

 V20 (%)

81.97 ± 4.24

67.99 ± 2.74*

53.81 ± 1.84*†

56.51 ± 1.59*†

 V30 (%)

58.72 ± 4.66

40.41 ± 2.12*

33.34 ± 1.49*†

33.82 ± 1.56*†

 V40 (%)

35.01 ± 3.76

23.00 ± 2.44*

20.60 ± 1.93*†

20.75 ± 2.22*†

 V50 (%)

14.11 ± 2.42

11.22 ± 1.86*

10.69 ± 1.75*

10.63 ± 1.74*

LSBM

 Dmean (Gy)

44.55 ± 1.54

38.81 ± 1.98*

43.37 ± 1.48*

35.51 ± 0.30*

 V10 (%)

99.98 ± 0.07

99.77 ± 0.69

99.98 ± 0.07

99.05 ± 1.47*†

 V20 (%)

99.21 ± 1.52

92.14 ± 5.07*

98.86 ± 1.48†

80.97 ± 2.51*†

 V30 (%)

94.99 ± 3.18

76.59 ± 7.81*

92.79 ± 3.35†

64.46 ± 1.33*†

 V40 (%)

75.70 ± 8.58

51.47 ± 6.89*

69.51 ± 8.60*†

44.54 ± 3.06*†

 V50 (%)

30.90 ± 5.27

23.63 ± 3.88*

28.12 ± 4.34*†

21.74 ± 2.71*

  1. Abbreviations: IMRT (N) Without bone marrow as avoidance structures, IMRT (BM) Whole bone marrow as avoidance structures, IMRT (OC) Os coxae as avoidance structures, IMRT (OC + LS) Both os coxae and lumbosacral spine as avoidance structures, BM Bone marrow, OC Os coxae, LS Lumbosacral spine, Dmean the mean dose, Vn percentage of volume receiving n Gy
  2. *p value < 0.05 while comparing IMRT (N) plan with other three plans
  3. †p value < 0.05 while comparing IMRT (BM) plan with IMRT (OC) and IMRT (OC + LS) plans, respectively