Skip to main content

Advertisement

Table 4 Dosimetric comparison for BM, OC and LS

From: Optimal dose limitation strategy for bone marrow sparing in intensity-modulated radiotherapy of cervical cancer

Parameters IMRT (N) IMRT (BM) IMRT (OC) IMRT (OC + LS)
BM
 Dmean (Gy) 37.57 ± 1.11 32.14 ± 0.25* 32.07 ± 0.61* 29.40 ± 0.52*†
 V10 (%) 97.62 ± 1.98 95.46 ± 2.04* 92.72 ± 2.51*† 92.74 ± 2.31*†
 V20 (%) 88.38 ± 2.87 76.88 ± 1.99* 70.58 ± 2.00*† 65.67 ± 1.44*†
 V30 (%) 72.17 ± 3.67 53.70 ± 1.54* 55.41 ± 2.20* 45.25 ± 1.50*†
 V40 (%) 50.03 ± 4.07 33.47 ± 1.70* 38.64 ± 2.83*† 29.63 ± 1.90*†
 V50 (%) 20.29 ± 2.42 15.79 ± 1.64* 17.11 ± 1.83* 14.77 ± 1.47*
OC
 Dmean (Gy) 33.46 ± 1.46 28.27 ± 0.93* 25.42 ± 0.46*† 25.78 ± 0.59*†
 V10 (%) 96.21 ± 3.15 92.94 ± 3.05* 88.47 ± 3.67*† 89.06 ± 3.31*†
 V20 (%) 81.97 ± 4.24 67.99 ± 2.74* 53.81 ± 1.84*† 56.51 ± 1.59*†
 V30 (%) 58.72 ± 4.66 40.41 ± 2.12* 33.34 ± 1.49*† 33.82 ± 1.56*†
 V40 (%) 35.01 ± 3.76 23.00 ± 2.44* 20.60 ± 1.93*† 20.75 ± 2.22*†
 V50 (%) 14.11 ± 2.42 11.22 ± 1.86* 10.69 ± 1.75* 10.63 ± 1.74*
LSBM
 Dmean (Gy) 44.55 ± 1.54 38.81 ± 1.98* 43.37 ± 1.48* 35.51 ± 0.30*
 V10 (%) 99.98 ± 0.07 99.77 ± 0.69 99.98 ± 0.07 99.05 ± 1.47*†
 V20 (%) 99.21 ± 1.52 92.14 ± 5.07* 98.86 ± 1.48† 80.97 ± 2.51*†
 V30 (%) 94.99 ± 3.18 76.59 ± 7.81* 92.79 ± 3.35† 64.46 ± 1.33*†
 V40 (%) 75.70 ± 8.58 51.47 ± 6.89* 69.51 ± 8.60*† 44.54 ± 3.06*†
 V50 (%) 30.90 ± 5.27 23.63 ± 3.88* 28.12 ± 4.34*† 21.74 ± 2.71*
  1. Abbreviations: IMRT (N) Without bone marrow as avoidance structures, IMRT (BM) Whole bone marrow as avoidance structures, IMRT (OC) Os coxae as avoidance structures, IMRT (OC + LS) Both os coxae and lumbosacral spine as avoidance structures, BM Bone marrow, OC Os coxae, LS Lumbosacral spine, Dmean the mean dose, Vn percentage of volume receiving n Gy
  2. *p value < 0.05 while comparing IMRT (N) plan with other three plans
  3. p value < 0.05 while comparing IMRT (BM) plan with IMRT (OC) and IMRT (OC + LS) plans, respectively