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Table 2 Results for all investigated metrics. While some metrics were investigated on a plan-wise basis (cumulative MU, and the brain receiving 4, 5 and 8 Gy) others were examined on a lesion-wise basis (V10Gy, V12Gy, conformity index, gradient index)

From: Single isocenter stereotactic radiosurgery for patients with multiple brain metastases: dosimetric comparison of VMAT and a dedicated DCAT planning tool

  MBSRS
DCAT
median (range)
  Monaco®
VMAT
median (range)
  P (Wilcoxon SR)
Plan data
N = 20
  # plans MBSRS superior   # plans VMAT superior  
Cumulative MU 4569 (3543–7790) 17 5840 (4089–10,769) 3 < 0.05
V4Gy (brain) [cm3] 45.6 (18.5–215.9) 19 123.1 (37.5–418.6) 1 < 0.05
V5Gy (brain) [cm3] 33.7 (13.0–120.5) 19 69.1 (26.0–273.6) 1 < 0.05
V8Gy (brain) [cm3] 17.4 (6.3–52.6) 19 26.6 (10.6–86.4) 1 < 0.05
PTV data
N = 59
  # PTVs MBSRS superior   # PTVs VMAT superior  
V10Gy (healthy brain) [cm3] 3.2 (0.4–19.3) 55 4.9 (1.0–19.9) 4 < 0.05
V12Gy (healthy brain) [cm3] 2.1 (0.1–13.1) 53 3.1 (0.5–13.9) 6 < 0.05
PTV data without PTVs overlapping in half prescribed isodose
N = 53
  # PTVs MBSRS superior   # PTVs VMAT superior  
Paddick CI 0.75 (0.58–0.89) 30 0.73 (0.38–0.88) 22 < 0.05
GIPTV 5.99 (3.50–15.73) 48 7.17 (3.35–33.00) 5 < 0.05