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Table 1 Clinical characteristics and treatment methods of evaluable patients

From: Management of orbital invasion in esthesioneuroblastoma: 14 years’ experience

Variable

No. (%)

Median age, yr. (range)

54 (22–77)

Sex

 Male

44 (73.3%)

 Female

16 (26.7%)

Degree of orbital invasiona

 Grade I

12 (20%)

 Grade II

23 (38.3%)

 Grade III

25 (41.7%)

Foote stage

 C

52 (86.7%)

 D

8 (13.3%)

Lymph node classification

 N0

52 (86.7%)

 N+

8 (13.3%)

Orbital symptoms

 Yes

41 (68.3%)

 No

19 (31.7%)

Treatment methods

 Radical radiation

14 (23.3%)

 Preoperative radiation + surgery

21 (35%)

 Postoperative radiation +surgery

25 (41.7%)

Surgical methods

 Endoscopic group

33 (71.7%)

 Open groupb

13 (28.3%)

Management of neck

 PENI

25 (41.6%)

 TENI

7 (11.7%)

 END

1 (1.7%)

 No management

27 (45%)

Type of radiotherapy

 3D-CRT

34 (56.7%)

 IMRT

26 (43.3%)

Chemotherapy

 Yes

47 (78.3%)

 No

13 (21.7%)

  1. Abbreviation: 3D-CRT three-dimensional conformal radiotherapy, IMRT intensity-modulated radiotherapy, PENI prophylactic elective neck irradiation, TENI therapeutic elective neck irradiation, END elective neck dissection
  2. aGrade I, bone wall erosion; grade II, invasion of extraconal fat; grade III, involvement of extraocular muscles, eye globe, orbital apex, or optic nerve
  3. bOpen group included lateral rhinotomy and craniofacial resection