From: Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results
 | Planning Volumes | Definition | Doses by Fractionation Scheme | |
---|---|---|---|---|
15-Fraction | 25-Fraction | |||
Prescriptions | Microscopic Extension PTV | CTV + 5 mm CTV = GTV + 1 cm + CA, SMA, +/− porta hepatis, +/− splenic hilum basins | 37.5Gy/15 | 45Gy/25 |
High Dose PTV | GTV + 0-5 mm margin excluding GI OAR + 5–7 margin | 67.5Gy/15 | 75Gy/25 | |
Ultra High Dose PTVa | 1 cm contraction of High Dose PTV | 90Gy/15 | 100Gy/25 | |
Constraints | Stomach-Duodenum PRV | Stomach and duodenum segments 1 and 2 + 3-5 mm | Dmax <45Gy | Dmax <60Gy |
Small Bowel PRV | All other small bowel + 3-5 mm | Dmax <40Gy | Dmax <55Gy | |
Large Bowel PRV | Large bowel + 3-5 mm | Dmax <50Gy | Dmax <65Gy |