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Table 1 Baseline characteristics of the patients

From: Prophylactic NS-21 maintains the skin moisture but does not reduce the severity of radiation dermatitis in patients with head and neck cancer: a randomized control trial

Characteristic

Study group

(n = 15)

Control group

(n = 15)

p-value

Age (years)

 Mean ± SD

56.6 ± 10.4

56.9 ± 7.9

0.937a

 Range

41–82

38–71

 

Gender

  

1.000c

 Male

14 (93.3%)

14 (93.3%)

 

 Female

1 (6.7%)

1 (6.7%)

 

Education

  

0.705b

 Less than 12 years

9 (60.0%)

10 (66.7%)

 

 More than 12 years

6 (40.0%)

5 (33.3%)

 

Religion

  

0.709b

 Buddhist

7 (46.7%)

6 (40.0%)

 

 Taoist

5 (33.3%)

4 (26.7%)

 

 Christian

3 (20.0%)

5 (33.3%)

 

Marital status

  

0.390c

 Without a spouse

2 (13.3%)

5 (33.3%)

 

 With a spouse

13 (86.7%)

10 (66.7%)

 

Occupational status

  

0.450c

 Homemaking or part-time employment

8 (53.3%)

11 (73.3%)

 

 Employed

7 (46.7%)

4 (26.7%)

 

Habits related to cancer

 None

1 (6.7%)

3 (20.0%)

0.598c

 Alcohol use

9 (60.0%)

9 (60.0%)

1.000b

 Tobacco use

13 (86.7%)

11 (73.3%)

0.651c

 Betel nut use

9 (60.0%)

7 (46.7%)

0.464b

Radiation modalities

 Versa HD™

8 (53.3%)

9 (60.0%)

0.713b

 Helical tomotherapy

7 (46.7%)

6 (40.0%)

 

Comorbidity

 None

9 (60.0%)

9 (60.0%)

1.000b

 Diabetes

3 (20.0%)

3 (20.0%)

1.000c

 Hypertension

4 (26.7%)

5 (33.3%)

1.000c

 Coronary artery disease

1 (6.7%)

0

1.000c

 Others

1 (6.7%)

2(13.4%)

 

Tumor site

 Nasopharyngeal cancer

4 (26.7%)

0

 

 Oral cancer

7(46.7%)

10 (66.7%)

 

 Oropharyngeal cancer

2 (13.3%)

3 (20.0%)

 

 Laryngeal cancer

0

1 (6.7%)

 

 Hypopharyngeal cancer

2 (13.3%)

1 (6.7%)

 

AJCC(7th edition) Stage

  

0.185b

 Stage I

1 (6.7%)

2 (13.3%)

 

 Stage II

5 (33.3%)

2 (13.3%)

 

 Stage III

5 (33.3%)

2 (13.3%)

 

 Stage IV

4 (26.7%)

9 (60.0%)

 

Surgery

  

0.128c

 Yes

7 (46.7%)

12 (80.0%)

 

 No

8 (53.3%)

3 (20.0%)

 

Chemotherapy

  

0.651c

 Yes

12 (80.0%)

11 (73.3%)

 

 No

3 (20.0%)

4 (26.7%)

 

Radiation dose

  

0.714a

 Mean

(± SD)

66.86

(± 4.20)

66.27

(± 3.85)

 

 Median

70

66

 

 Min,

60

60

 

 Max

70

70

 
  1. (aMann-Whitney U test, bChi-square test, cFisher exact test)