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Table 1 Baseline characteristics of the patients

From: Prophylactic NS-21 maintains the skin moisture but does not reduce the severity of radiation dermatitis in patients with head and neck cancer: a randomized control trial

Characteristic Study group
(n = 15)
Control group
(n = 15)
p-value
Age (years)
 Mean ± SD 56.6 ± 10.4 56.9 ± 7.9 0.937a
 Range 41–82 38–71  
Gender    1.000c
 Male 14 (93.3%) 14 (93.3%)  
 Female 1 (6.7%) 1 (6.7%)  
Education    0.705b
 Less than 12 years 9 (60.0%) 10 (66.7%)  
 More than 12 years 6 (40.0%) 5 (33.3%)  
Religion    0.709b
 Buddhist 7 (46.7%) 6 (40.0%)  
 Taoist 5 (33.3%) 4 (26.7%)  
 Christian 3 (20.0%) 5 (33.3%)  
Marital status    0.390c
 Without a spouse 2 (13.3%) 5 (33.3%)  
 With a spouse 13 (86.7%) 10 (66.7%)  
Occupational status    0.450c
 Homemaking or part-time employment 8 (53.3%) 11 (73.3%)  
 Employed 7 (46.7%) 4 (26.7%)  
Habits related to cancer
 None 1 (6.7%) 3 (20.0%) 0.598c
 Alcohol use 9 (60.0%) 9 (60.0%) 1.000b
 Tobacco use 13 (86.7%) 11 (73.3%) 0.651c
 Betel nut use 9 (60.0%) 7 (46.7%) 0.464b
Radiation modalities
 Versa HD™ 8 (53.3%) 9 (60.0%) 0.713b
 Helical tomotherapy 7 (46.7%) 6 (40.0%)  
Comorbidity
 None 9 (60.0%) 9 (60.0%) 1.000b
 Diabetes 3 (20.0%) 3 (20.0%) 1.000c
 Hypertension 4 (26.7%) 5 (33.3%) 1.000c
 Coronary artery disease 1 (6.7%) 0 1.000c
 Others 1 (6.7%) 2(13.4%)  
Tumor site
 Nasopharyngeal cancer 4 (26.7%) 0  
 Oral cancer 7(46.7%) 10 (66.7%)  
 Oropharyngeal cancer 2 (13.3%) 3 (20.0%)  
 Laryngeal cancer 0 1 (6.7%)  
 Hypopharyngeal cancer 2 (13.3%) 1 (6.7%)  
AJCC(7th edition) Stage    0.185b
 Stage I 1 (6.7%) 2 (13.3%)  
 Stage II 5 (33.3%) 2 (13.3%)  
 Stage III 5 (33.3%) 2 (13.3%)  
 Stage IV 4 (26.7%) 9 (60.0%)  
Surgery    0.128c
 Yes 7 (46.7%) 12 (80.0%)  
 No 8 (53.3%) 3 (20.0%)  
Chemotherapy    0.651c
 Yes 12 (80.0%) 11 (73.3%)  
 No 3 (20.0%) 4 (26.7%)  
Radiation dose    0.714a
 Mean
(± SD)
66.86
(± 4.20)
66.27
(± 3.85)
 
 Median 70 66  
 Min, 60 60  
 Max 70 70  
  1. (aMann-Whitney U test, bChi-square test, cFisher exact test)