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Table 3 Multivariate survival model for freedom from biochemical failure (FFBF); death unrelated to prostate carcinoma was censored and not counted as an event

From: Postoperative elective pelvic nodal irradiation compared to prostate bed irradiation in locally advanced prostate cancer – a retrospective analysis of dose-escalated patients

Variable Hazard Ratio 95% CI P
Elective pelvic radiotherapy (WPRT) 0.493 0.270–0.898 0.021
Detectable tumor and high-dose radiotherapy 0.525 0.259–1.063 0.073
Salvage radiotherapyc 1.547 0.745–3.215 0.242
Androgen-deprivation therapy (ADT-) usagea 0.673 0.254–1.786 0.427
PSA values at start of radiotherapy above 0.2 ng/ml 1.631 0.904–2.943 0.104
Higher Gleason score of surgical specimensb 1.441 1.080–1.922 0.013
  1. aExcluding ADT-usage as a variable in a sensitivity model did not change results (i.e. WPRT and Gleason remained significant predictors)
  2. bUsing the Roach score (cut-off of ≥25) instead of Gleason scores did not change the overall model and did not influence WPRT as a significant predictor
  3. cInclusion of the S-RT-Interval which was not significant in the bPFS univariate model but in the FFBF analysis did not change the overall model and did not influence WPRT as a significant predictor