Postoperative elective pelvic nodal irradiation compared to prostate bed irradiation in locally advanced prostate cancer – a retrospective analysis of dose-escalated patients

Table 2 Multivariate survival model for biochemical progression-free survival (bPFS)

Variable	Hazard Ratio	95% CI	P
Elective pelvic radiotherapy (WPRT)	0.484	0.270–0.870	0.015
Detectable tumor and high-dose radiotherapy	0.517	0.257–1.038	0.064
Salvage radiotherapy^c	1.444	0.704–2.962	0.316
Androgen-deprivation therapy (ADT-) usage^a	0.764	0.310–1.881	0.558
PSA values at start of radiotherapy above 0.2 ng/ml	1.503	0.850–2.658	0.161
Higher Gleason score of surgical specimens^b	1.491	1.128–1.973	0.005

^aExcluding ADT-usage as a variable in a sensitivity model did not change results (i.e. WPRT and Gleason remained significant predictors)
^bUsing the Roach score (cut-off of ≥25) instead of Gleason scores did not change the overall model and did not influence WPRT as a significant predictor
^cInclusion of the S-RT-Interval which was not significant in the bPFS univariate model but in the FFBF analysis did not change the overall model and did not influence WPRT as a significant predictor

ISSN: 1748-717X