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Table 2 Multivariate survival model for biochemical progression-free survival (bPFS)

From: Postoperative elective pelvic nodal irradiation compared to prostate bed irradiation in locally advanced prostate cancer – a retrospective analysis of dose-escalated patients

Variable Hazard Ratio 95% CI P
Elective pelvic radiotherapy (WPRT) 0.484 0.270–0.870 0.015
Detectable tumor and high-dose radiotherapy 0.517 0.257–1.038 0.064
Salvage radiotherapyc 1.444 0.704–2.962 0.316
Androgen-deprivation therapy (ADT-) usagea 0.764 0.310–1.881 0.558
PSA values at start of radiotherapy above 0.2 ng/ml 1.503 0.850–2.658 0.161
Higher Gleason score of surgical specimensb 1.491 1.128–1.973 0.005
  1. aExcluding ADT-usage as a variable in a sensitivity model did not change results (i.e. WPRT and Gleason remained significant predictors)
  2. bUsing the Roach score (cut-off of ≥25) instead of Gleason scores did not change the overall model and did not influence WPRT as a significant predictor
  3. cInclusion of the S-RT-Interval which was not significant in the bPFS univariate model but in the FFBF analysis did not change the overall model and did not influence WPRT as a significant predictor