Fig. 6

Part (a) shows the dose distribution to a lesion planned using the ITV method. Part (b) shows the re-plan using the motion managed PTV, at the same prescription level as in (a). Part (c) shows the escalation of dose, from 42.5 Gy to 50 Gy (78.6 Gy₁₀ to 100 Gy₁₀), whilst adhering to OAR dose tolerances. Part (d) is a DVH demonstating PTV coverage (solid lines) for the three cases shown in (a) – (c), as well as liver dose (broken lines). ITV – ITV-based, MM – motion managed, MM esc – dose escalated motion management