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Table 2 Univariate and multivariate Cox regression analysis for 6-year biochemical failure in IR patients treated with RT alone

From: Radiotherapy with or without androgen deprivation therapy in intermediate risk prostate cancer?

Characteristic Covariate type Number at risk Cumulative probability of biochemical failure Univariate analysis Multivariate analysis
HR P 95% C.I. HR P 95% C.I.
Lower Upper Lower Upper
Age ≤ 70 years Categorical 56 17.9% 3.32 0.018 1.226 8.464 3.06 0.025 1.153 8.138
Pretreatment PSA (ng/mL) Continuous 177   1.03 0.684 0.899 1.176     
Gleason score Categorical 177          
 5 or 6   35 5.7% 1 reference       
 7 (3 + 4)   93 6.5% 1.16 0.852 0.235 5.772 1.42 0.667 0.285 7.128
 7 (4 + 3)   49 18.4% 3.16 0.141 0.685 14.656 3.32 0.125 0.717 15.383
T- stage T2b to T2c Categorical 61 11.5% 1.73 0.280 0.641 4.664     
No. IR risk factors Categorical 177          
 1   115 8.7% 1 reference       
 2   55 10.9% 1.76 0.278 0.635 4.856     
 3   7 14.3% 2.87 0.319 0.361 22.750     
Positive biopsy cores (%) Continuous 154   1 0.917 0.981 1.022     
Charlson comorbidity index Categorical 162          
 2   69 11.6% 1 reference       
 3   27 0% 0.00 0.977 0.000 0.000     
 ≥4   49 10.9% 0.72 0.836 0.309 2.261