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Fig. 6 | Radiation Oncology

Fig. 6

From: Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy

Fig. 6

Clonogenic assay for clinical-like fields (SOBPs) for the Renca cell line in experiment B. MC simulation estimated LETd values of biological measurement were ~ 5 keV·μm−1, ~ 10 keV·μm−1, ~ 15 keV·μm−1, ~ 27 keV·μm−1. FLUKA-coupled biophysical and phenomenological models predicted cell survival (a) and corresponding RBE (b) with varying degree of accuracy as a function of dose. The dotted and solid black line represent the LQ-fit of the Renca cells photon irradiation and 4He irradiation, respectively. LQ-fit parameters for the four LETd conditions are listed in the Table 2

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Radiation Oncology

ISSN: 1748-717X

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