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Table 1 Baseline characteristics of included studies

From: Efficacy and safety of intensity-modulated radiation therapy versus three-dimensional conformal radiation treatment for patients with gastric cancer: a systematic review and meta-analysis

Author

Year

N

Sex(Male/Female)

Age

Disease status

Surgery

N in IMRT

N in 3D-CRT (Gy)

Dose of IMRT (Gy)

Dose of 3D-CRT

Fraction of IMRT

Fraction of 3D-CRT

Chemotherapy

Type

Stage (AJCC)

Xin Wang [22]

2016

100

82/28

55 (23–73)

stage IB-IIIC gastric cancer

curative resection with D2 lymph node dissection

42

68

50.4

50.4

28

28

5-FU+ CDDP

RCT

IB-IIIC

A. Yuriko Minn [29]

2010

57

38/19

58 (29–83)

gastric or gastroesophageal junction cancer

Esophagogastrectomy, total or subtotal gastrectomy

31

26

45

45

25

25

5-FU+ CDDP

RS

I-III

Gene-Fu F. Liu [26]

2014

24

18/6

56–64

stage IB-IIIB gastric cancer

Esophagogastrectomy, total or subtotal gastrectomy

12

12

50.4

45

25

25

5-FU

RS

IB-IIIC

Boda-Heggemann J [12]

2009

60

37/23

35–75

gastric or gastroesophageal junction cancer

D2 resection

33

27

45

45

25

25

5-FU+ CDDP

RS

I-IV

Boda-Heggemann J [34]

2013

65

38/27

35–76

gastric or gastroesophageal junction cancer

total or subtotal gastrectomy

38

27

45

45

25

25

5-FU+ CDDP

RS

I-IV

Chopra S [23]

2015

51

35/16

54 (25–74)

gastric or, proximal gastric and gastro-esophageal junction cancer

total or subtotal gastrectomy

26

25

45

45

25

25

Capecitabine

RS

I-III

Goody, R. B. [35]

2016

55

30/25

54 (28–77)

completely resected gastric cancer

total or subtotal gastrectomy

NA

NA

45

45

25

25

cisplatin

PS

I-III

Fang, L. [25]

2015

75

54/21

47 (31–58)

stage III-IV gastric cancer

curative resection

25

25

45

45

NA

NA

None

RCT

III-IV

Deng, Q. H. [36]

2011

29

23/6

55 (29–72)

stage III-IV gastric cancer

total or subtotal gastrectomy

29

29

45

45

25

25

None

RS

III-IV (UICC)

  1. Abbreviation: N number, IMRT intensity modulated radiation therapy, 3D-CRT three-dimensional conformal radiation treatment, RCT randomized controlled trial, 5-Fu 5-fluorouracil, NA not available, RS retrospective study, PS prospective study, AJCC American Joint Committee on Cancer, UICC UnionInternationale Against Cancer