Table 3 Comparison of patient characteristics
No LLLT/PBMT (n = 32) | LLLT/PBMT (active or placebo) (n = 51) | p-value | ||
|---|---|---|---|---|
Gender | Female | 6 (18.8%) | 2 (3.9%) | 0.05006 |
Male | 26 (81.3%) | 49 (96.1%) | ||
Age (years) | Mean ± SD | 57.5 (52.7–64.5) | 59 (53–65) | 0.97 |
Tumour Location | Oral cavity | 8 (25%) | 9 (17.6%) | 0.60 |
Hypopharynx | 8 (25.0%) | 11 (21.6%) | ||
Oropharynx | 16 (50.0%) | 31 (60.8%) | ||
TNM classification | T1 | 5 (15.6%) | 2 (3.9%) | 0.20 |
T2 | 8 (25.0%) | 16 (31.4%) | ||
T3 | 10 (31.2%) | 24 (47.1%) | ||
T4a | 7 (21.9%) | 6 (11.8%) | ||
T4b | 2 (6.2%) | 3 (5.9%) | ||
N0 | 3 (9.4%) | 12 (23.5%) | 0.25 | |
N1 | 3 (9.4%) | 3 (5.9%) | ||
N2 | 24 (75.0%) | 32 (62.7%) | ||
N3 | 1 (3.1%) | 4 (7.8%) | ||
Nx | 1 (3.1%) | 0 (0%) | ||
Histologic differentiation | Well-differentiated | 15 (46.9%) | 21 (41.2%) | 0.95 |
Unknown | 2 (6.3%) | 4 (7.8%) | ||
Moderately differentiated | 12 (37.5%) | 19 (37.3%) | ||
Poorly differentiated | 3 (9.4%) | 7 (13.7%) | ||
Smoking status | Never-smokers | 4 (12.5%) | 8 (15.7%) | 0.94 |
Smokers | 28 (87.5%) | 43 (84.3%) | ||
During CRT | Smoking cessation | 1 (7.7%) | 7 (38.9%) | 0.095 |
Active smokers | 12 (92.3%) | 11 (61.1%) | ||
Alcohol consumption | No | 9 (28.1%) | 13 (25.5%) | 0.64 |
Unknown | 2 (6.3%) | 1 (2.0%) | ||
Yes | 21 (65.6%) | 37 (72.5%) | ||
During CRT | Alcohol withdrawal | 3 (33.3%) | 5 (25.0%) | 0.99 |
Active alcohol use | 6 (66.7%) | 15 (75.0%) | ||
Feeding | Enteral feeding | 4 (12.5%) | 5 (9.8%) | 0.84 |
Liquid diet | 0 (0%) | 1 (2.0%) | ||
Minced food | 7 (21.9%) | 16 (31.4%) | (binary | |
Unspecified | 2 (6.3%) | 0 (0%) | data) | |
Solid diet | 19 (59.4%) | 29 (56.9%) |