Fig. 1From: Technical feasibility of [18F]FET and [18F]FAZA PET guided radiotherapy in a F98 glioblastoma rat modelSchematic illustration of the different volumes as defined in ICRU Report 50. Gross tumor volume (GTV) denotes the demonstrated tumor. Clinical target volume (CTV) takes the tumor infiltration outside the GTV into account. The planning target volume (PTV) consists of the CTV and a margin to account for the interfractional and intrafractional variations [10]. Reproduced with permission of the International Commission on Radiation Units and Measurements, https://ICRU.orgBack to article page