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Table 1 Model fitting results of in vitro measurements of the change in the radiosensitivity of cancer cell cultures after exposure to fractionated radiation. Effect of different fractionation regimens on the mean α/β ratio and SF2 value. For each cell line the corresponding reference of the study is provided as superindexes

From: Modeling the effect of intratumoral heterogeneity of radiosensitivity on tumor response over the course of fractionated radiation therapy

Cell Line Total Dose Number of Fractions α/β before treatment α/β end of streatment SF2 before treatment SF2 end of treatment
PC3 31 10 Gy 5 22.1 ± 7.0 Gy 16.6 ± 6.2 Gy 0.40 ± 0.09 0.50 ± 0.10
LNCaP 31 10 Gy 5 18.0 ± 6.5 Gy 12.5 ± 5.9 Gy 0.47 ± 0.10 0.58 ± 0.12
Du145 31 10 Gy 5 15.5 ± 6.3 Gy 10.1 ± 5.5 Gy 0.52 ± 0.11 0.64 ± 0.12
A549 32 16 Gy 8 10.2 ± 3.3 Gy 5.4 ± 2.7 Gy 0.44 ± 0.10 0.61 ± 0.11
H460 32 26 Gy 13 3.1 ± 1.1 Gy 1.2 ± 0.8 Gy 0.46 ± 0.08 0.61 ± 0.07
OE33 30 50 Gy 25 20.6 ± 5.1 Gy 13.7 ± 3.2 Gy 0.42 ± 0.05 0.56 ± 0.04