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Table 3 Univariate logistic regression of dosimetric factors and postoperative adverse events

From: Prognostic significance of lung radiation dose in patients with esophageal cancer treated with neoadjuvant chemoradiotherapy

  Pulmonary complicationsa Cardiac complicationsb 30-day mortality 60-day mortality
Characteristics OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Gross tumor volume 1.00 (0.99–1.01) 0.17 1.00 (0.99–1.00) 0.67 1.00 (0.98–1.02) 0.92 1.01 (1.00–1.02) 0.09
Target volume 1.00 (1.00–1.00) 0.20 1.00 (0.99–1.00) 0.39 1.00 (0.98–1.01) 0.24 1.00 (0.99–1.01) 0.92
Radiation dose 1.00 (1.00–1.00) 0.83 1.00 (1.00–1.00) 0.61 1.00 (1.00–1.00) 0.90 1.00 (1.00–1.00) 0.88
DVH of lungc
 V5 1.02 (1.00–1.04) 0.03 0.98 (0.95–1.02) 0.32 1.04 (0.97–1.12) 0.32 1.04 (0.98–1.11) 0.22
 V20 0.99 (0.93–1.05) 0.72 0.94 (0.82–1.07) 0.35 1.00 (0.79–1.16) 0.65 0.99 (0.85–1.16) 0.91
 Mean heart dose 1.00 (1.00–1.00) 0.82 0.99 (1.00–1.00) 0.13 1.00 (1.00–1.00) 0.71 1.00 (1.00–1.00) 0.31
  1. Abbreviations: CI confidence interval, DVH dose-volume histogram, GTV gross tumor volume, OR odds ratio
  2. aAny grade
  3. bGrade ≥ 3 complications. The 7 patients had grade 3 cardiac dysrhythmia were analyzed
  4. cVx = volume (mL) of lung receiving X Gy or more