|
Event
|
Any grade, n (%)
|
Grade ≥ 3, n (%)
|
|---|
|
Postoperative events
|
|
Pulmonary complicationsa
|
36 (27.6%)
|
15 (12.2)
|
|
Cardiac complicationsc
|
21 (17.1%)
|
7 (5.7)
|
|
Chylothorax
|
15 (12.2)
|
2 (1.6)
|
|
Anastomotic leakage
|
21 (17.1)
|
9 (7.3)
|
|
Postoperative mortalityb
|
|
7 days
|
0 (0)
|
–
|
|
30 days
|
3 (2.4%)
|
–
|
|
60 days
|
1 (0.8%)
|
–
|
|
Events during chemoradiotherapy
|
|
Hematological toxicityd
|
113 (91.9)
|
54 (43.9)
|
|
Weight loss
|
101 (82.1)
|
21 (17.1)
|
|
Esophagitis
|
114 (92.7)
|
1 (0.8)
|
|
Radiation pneumonitis
|
56 (45.5)
|
0 (0)
|
|
Fatigue
|
77 (62.6)
|
0 (0)
|
- aPulmonary complications included pneumonia, serious atelectasis, pneumothorax, pleural effusion, pulmonary embolus, and acute respiratory failure
- bThe causes of postoperative mortality for the 4 patients were all postoperative complication of sepsis
- cCardiac complications included dysrhythmia, myocardial infarction, and left ventricular failure. All of 7 patients had grade 3 cardiac dysrhythmia; no patients had grade ≥ 4 cardiac complications
- dHematological toxicity included leukopenia, neutropenia, and thrombocytopenia
