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Table 1 Patient and tumor characteristics

From: Prognostic significance of lung radiation dose in patients with esophageal cancer treated with neoadjuvant chemoradiotherapy

Characteristics

Overall (n = 123)

Age (years), mean ± SD

54.3 ± 7.6

Sex, n (%)

 Man

117 (95.1)

 Woman

6 (4.9)

ECOG performance status, n (%)

 0

105 (85.4)

 1

18 (14.6)

Pathology, n (%)

 SCC

120 (97.6)

 Adenocarcinoma

3 (2.4)

Location, n (%)

 Upper

24 (19.5)

 Middle

59 (48.0)

 Lower

40 (32.5)

BMI (kg/m2), mean ± SD

22.1 ± 3.3

Histologic grade, n (%)

 Grade 1

12 (9.8)

 Grade 2

88 (71.5)

 Grade 3

23 (18.7)

Smoking, n (%)

 No (never smoked or quitted)

7 (5.7)

 Yes (current smoker)

116 (94.3)

Clinical T stage, n (%)

 cT1

1 (0.8)

 cT2

36 (29.3)

 cT3

80 (65.0)

 cT4a

6 (4.9)

Clinical N stage, n (%)

 cN0

14 (11.4)

 cN1

57 (46.3)

 cN2

39 (31.7)

 cN3

13 (10.6)

cTNM stage, n (%)

 II

31 (25.2)

 III

92 (74.8)

Gross tumor volume (ml), mean ± SD

100.9 ± 73.2

Radiation dose (Gy), median (IQR)

44.0 (43.2–45.0)

 40–44 Gy, n(%)

62 (50.4)

 45–50.4 Gy, n(%)

61 (49.6)

Target volume (ml), mean ± SD

527.6 ± 228.5

Dose-volume of lunga (%), mean ± SD

 V5

74.0 ± 21.2

 V20

20.8 ± 6.4

Mean heart dose (Gy), mean ± SD

18.3 ± 7.6

  1. Abbreviations: BMI body mass index, ECOG Eastern Cooperative Oncology Group, IQR interquartile range, SCC squamous cell carcinoma, SD standard deviation
  2. aVx = volume (mL) of lung receiving X Gy or more