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Table 1 Summary Rationale For Neoadjuvant Chemo-RT Versus Adjuvant Chemo For Pancreatic Adenocarcinoma

From: Radiation therapy for pancreatic adenocarcinoma, a treatment option that must be considered in the management of a devastating malignancy

Comparator Variable Neoadjuvant Chemo-RT Up-front Surgery + Adjuvant Chemo Citations to Support
Rate of Positive Margins 2–20% 16–60% [16,17,18,19]
Incidence of Node Positivity 17–40% 62–80% [13, 16, 17, 20]
Successful Treatment completion 70–80% 50–60% [17, 21, 22]
Rates of Local Recurrence 5–15% 19–53% [13, 17, 18, 23]