Characteristics | Total | < 28 Days (early n = 51) | 28–33 Days (regular n = 52) | > 33 Days (late n = 48) | p Value |
---|---|---|---|---|---|
Age, ya | 60.3+/−11.9 | 61.4+/−7.8 | 60.2+/−12.1 | 62.2+/−12.1 | 0.964 |
Male | 96(64%) | 30 (59%) | 31(60%) | 35(73%) | 0.265 |
KPSb | 90 | 90 | 90 | 90 | 0.521 |
KPS < 70 | 11(7.3%) | 3(6%) | 5(10%) | 3(6%) | 0.725 |
Preoperative symptoms | |||||
 Duration of symptoms, daysb | 3(1–48) | 4(1–40) | 3(1–48) | 3(1–48) | 0.736 |
 Headache | 52(34%) | 15(29%) | 22(42%) | 15(31%) | 0.331 |
 Nausea/vomiting | 18(12%) | 5(10%) | 7(14%) | 6(13%) | 0.839 |
 Motor deficit | 71(47%) | 28(55%) | 24(46%) | 19(40%) | 0.308 |
 Sensory deficit | 16(11%) | 9(18%) | 4(8%) | 3(6%) | 0.129 |
 Seizures | 54(36%) | 20(39%) | 19(37%) | 15(31%) | 0.703 |
 Language deficit | 54(36%) | 20(39%) | 20(39%) | 14(29%) | 0.512 |
 Visual impairment | 28(19%) | 7(14%) | 9 (17%) | 12(25%) | 0.339 |
 Ataxia/gait deficit | 58(38%) | 20(39%) | 19(37%) | 19(40%) | 0.942 |
 Cognitive deficit | 72(48%) | 24(47%) | 28 (54%) | 20(42%) | 0.473 |
 Altered level of consciousness | 5(3%) | 0(0%) | 3(6%) | 2(4%) | 0.242 |
Radiographic characteristics | |||||
 Midline structures involvement (FLAIR) | 22(15%) | 8(16%) | 9(17%) | 5(10%) | 0.598 |
 Left hemisphere | 74(49%) | 24(47%) | 23(44%) | 27(56%) | 0.458 |
 Preoperative tumor volume, cm3b | 22.4(1.4- | 24.8(1.4- | 20.4(2.3–122.7) | 18.7(1.5–96) | 0.769 |
122.7) | 112.7) | Â | Â | Â | |
 Residual tumor volume, cm3b | 0.1(0–13.1) | 0.5 (0–11.8) | 0.1 (0–7.9) | 0(0–13.1) | 0.128 |
 Extent of resectionb | 100%(32.7- | 99%(73- | 100%(33–100%) | 100%(79- | 0.101 |
100) | 100%) | Â | 100%) | Â | |
Miscellaneous | |||||
 Duration of hospitalization, daysb | 8(3–40) | 8(5–29) | 7(3–18) | 9(4–40) | 0.017 |
 Duration of the operation, minb | 222(94–524) | 206(94–524) | 224(100–405) | 225(140- | 0.584 |
 |  |  | 419) |  | |
 Ki-67b | 20 | 30 | 20 | 20 | 0.840 |
 Ki-67 < 15 | 23(15%) | 7(14%) | 10(19%) | 6(13%) | 0.622 |
 MGMT negative | 89(59%) | 31(62%) | 34(65%) | 24(51%) | 0.322 |
 Survival, monthsc | 17.3(13.7–20.9) | 15(11.5–18.5) | 17.4(10.7–24.1) | 18,2(12.9–23.5) | 0.902 |