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Table 2 Patient characteristics (Terciles)

From: Impact of time to initiation of radiotherapy on survival after resection of newly diagnosed glioblastoma

Characteristics

Total

< 28 Days (early n = 51)

28–33 Days (regular n = 52)

> 33 Days (late n = 48)

p Value

Age, ya

60.3+/−11.9

61.4+/−7.8

60.2+/−12.1

62.2+/−12.1

0.964

Male

96(64%)

30 (59%)

31(60%)

35(73%)

0.265

KPSb

90

90

90

90

0.521

KPS < 70

11(7.3%)

3(6%)

5(10%)

3(6%)

0.725

Preoperative symptoms

 Duration of symptoms, daysb

3(1–48)

4(1–40)

3(1–48)

3(1–48)

0.736

 Headache

52(34%)

15(29%)

22(42%)

15(31%)

0.331

 Nausea/vomiting

18(12%)

5(10%)

7(14%)

6(13%)

0.839

 Motor deficit

71(47%)

28(55%)

24(46%)

19(40%)

0.308

 Sensory deficit

16(11%)

9(18%)

4(8%)

3(6%)

0.129

 Seizures

54(36%)

20(39%)

19(37%)

15(31%)

0.703

 Language deficit

54(36%)

20(39%)

20(39%)

14(29%)

0.512

 Visual impairment

28(19%)

7(14%)

9 (17%)

12(25%)

0.339

 Ataxia/gait deficit

58(38%)

20(39%)

19(37%)

19(40%)

0.942

 Cognitive deficit

72(48%)

24(47%)

28 (54%)

20(42%)

0.473

 Altered level of consciousness

5(3%)

0(0%)

3(6%)

2(4%)

0.242

Radiographic characteristics

 Midline structures involvement (FLAIR)

22(15%)

8(16%)

9(17%)

5(10%)

0.598

 Left hemisphere

74(49%)

24(47%)

23(44%)

27(56%)

0.458

 Preoperative tumor volume, cm3b

22.4(1.4-

24.8(1.4-

20.4(2.3–122.7)

18.7(1.5–96)

0.769

122.7)

112.7)

   

 Residual tumor volume, cm3b

0.1(0–13.1)

0.5 (0–11.8)

0.1 (0–7.9)

0(0–13.1)

0.128

 Extent of resectionb

100%(32.7-

99%(73-

100%(33–100%)

100%(79-

0.101

100)

100%)

 

100%)

 

Miscellaneous

 Duration of hospitalization, daysb

8(3–40)

8(5–29)

7(3–18)

9(4–40)

0.017

 Duration of the operation, minb

222(94–524)

206(94–524)

224(100–405)

225(140-

0.584

   

419)

 

 Ki-67b

20

30

20

20

0.840

 Ki-67 < 15

23(15%)

7(14%)

10(19%)

6(13%)

0.622

 MGMT negative

89(59%)

31(62%)

34(65%)

24(51%)

0.322

 Survival, monthsc

17.3(13.7–20.9)

15(11.5–18.5)

17.4(10.7–24.1)

18,2(12.9–23.5)

0.902

  1. aMean ± SD
  2. bMedian
  3. cKaplan-Meier estimate of median postoperative survival