Table 4 Multivariate Cox regression analysis
Parameter | OS HR [95% CI] | p-value | PFS HR [95% CI] | p-value | LR HR [95% CI] | p-value |
|---|---|---|---|---|---|---|
Treatment Regimen (nCRT + S vs. dCRT) | 1.453 [0.688; 3.070] | 0.327 | 1.135 [0.592; 2.175] | 0.704 | 0.434 [0.136; 1.382] | 0.158 |
Age (continuous) | 1.064 [1.019; 1.110] | 0.005 | 1.054 [1.016; 1.093] | 0.005 | 1.041 [0.984; 1.101] | 0.165 |
Sex (female vs. male) | 0.634 [0.316; 1.273] | 0.200 | 0.696 [0.370; 1.311] | 0.263 | 0.763 [0.277; 2.100] | 0.601 |
Tumor lengths, cm (continuous) | 1.044 [0.933; 1.168] | 0.451 | 1.033 [0.932; 1.145] | 0.541 | 1.057 [0.912; 1.224] | 0.462 |
Tumor location (continuous) | 0.939 [0.884; 0.998] | 0.043 | 0.925 [0.876; 0.976] | 0.005 | 0.843 [0.760; 0.935] | 0.001 |
T-stage (Tis/T1/2 vs. T3/4) | 1.434 [0.639; 3.221] | 0.383 | 1.118 [0.527; 2.369] | 0.772 | 1.997 [0.665; 5.993] | 0.217 |
N-stage (N0 vs N1) | 1.556 [0.558; 4.337] | 0.398 | 0.821 [0.302; 2.234] | 0.699 | 0.605 [0.135; 2.702] | 0.510 |
Grading (G1/2 vs. G3) | 2.674 [1.299; 4.503] | 0.008 | 2.034 [1.098; 3.768] | 0.024 | 2.322 [0.835; 6.453] | 0.106 |