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Table 3 Univariate Cox regression analysis

From: Neoadjuvant versus definitive chemoradiation in patients with squamous cell carcinoma of the esophagus

Parameter OS HR [95% CI] p-value PFS HR [95% CI] p-value LR HR [95% CI] p-value
Treatment Regimen (nCRT + S vs. dCRT) 0.690 [0.377; 1.264] 0.230 0.643 [0.374; 1.107] 0.111 0.199 [0.068; 0.582] 0.003
Age (continuous) 1.025 [0.990; 1.061] 0.160 1.025 [0.994; 1.057] 0.115 1.009 [0.966; 1.053] 0.699
Sex (female vs. male) 0.830 [0.446; 1.545] 0.557 0.807 [0.462; 1.410] 0.451 0.775 [0.334; 1.80] 0.553
Tumor lengths, cm (continuous) 0.996 [0.899; 1.104] 0.946 1.012 [0.925; 1.107] 0.798 1.022 [0.895; 1.167] 0.744
Tumor location (continuous) 0.954 [0.907; 1.004] 0.069 0.940 [0.897; 0.985] 0.010 0.844 [0.773; 0.921] < 0.001
T-stage (Tis/T1/2 vs. T3/4) 1.295 [0.618; 2.714] 0.493 0.966 [0.485; 1.924] 0.921 1.319 [0.524; 3.316] 0.557
N-stage (N0 vs N1) 1.780 [0.965; 4.560] 0.230 1.167 [0.464; 2.935] 0.743 1.207 [0.284; 5.136] 0.799
Grading (G1/2 vs. G3) 2.059 [1.084; 3.911] 0.027 1.673 [0.961; 2.912] 0.069 2.065 [0.882; 4.837] 0.095
  1. IQR inter-quartiles-range, OS overall survival, PFS progression-free survival, LR local recurrence, HR Hazard ratio, CI Confidence interval