Table 1 Patients’ baseline and tumor parameters
Parameter | nCRT + S (n = 40) | dCRT (n = 55) | p-value |
|---|---|---|---|
Age, (years) | |||
Median | 65 | 68 | 0.079 |
IQR | 56–72 | 62–74 | |
Male sex | 22 (55%) | 40 (73%) | 0.085 |
T-stage (cT) | |||
Tis | 0 (0%) | 1 (2%) | 0.148 |
T1 | 1 (3%) | 3 (5%) | |
T2 | 7 (18%) | 8 (15%) | |
T3 | 32 (80%) | 37 (67%) | |
T4 | 0 (0%) | 6 (11%) | |
N-stage (cN) | |||
N+ | 40 (100%) | 47 (85%) | 0.019 |
Grading | |||
G1 | 1 (3%) | 0 (0%) | 0.729 |
G2 | 20 (53%) | 26 (53%) | |
G3 | 17 (45%) | 23 (47%) | |
Tumor length, (cm) | |||
Median | 5 | 5 | 0.445 |
IQR | 3–7 | 4–7 | |
Distance from dental arch to cranial tumor border, (cm) | |||
Median | 26 | 20 | < 0.001 |
IQR | 24–30 | 17–26 | |
Tumor location | |||
Cervical | 4 (10%) | 26 (47%) | < 0.001 |
Thoracic | 35 (88%) | 28 (51%) | |
Abdominal | 1 (3%) | 1 (2%) | |
Cumulative RT dose, (Gy) | |||
Median | 41.4 | 54 | < 0.001 |
IQR | 41.4–45 | 54–59.4 | |
Complete tumor resection | 36 (97%) | – | – |