Post-radiation sinusitis is associated with recurrence in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy

Table 2 Univariate analysis of prognostic factors

	3 yr. OS (%)	p	3 yr. DFS (%)	p	3 yr. FFLF (%)	p	3 yr. FFDF (%)	p
Gender		0.025		0.009		0.06		0.018
Male	89		76.3		89		84.9
Female	100		94.4		96.3		96.8
Age		0.049		0.049		0.108		0.18
< 40y/o	88.9		89.9		96.3		93.7
> 40y/o	88.4		76.7		88.5		85.2
T classification		0.002		< 0.001		< 0.001		0.012
T1–3	94		84		93.8		89.4
T4	72.2		54.1		66.5		73.7
N classification		0.001		< 0.001		0.654		< 0.001
N0–2	93.1		82.8		89.8		90.2
N3	71.6		51.7		88.9		57.4
Chemotherapy		0.083		0.036		0.543		0.085
No	100		88.9		88.9		94.4
Yes	90		78.5		90.7		86.1
Pre-radiation sinusitis		0.048		0.002		0.057		0.082
No	96.4		89.4		93.7		91.4
Yes	87.1		72.5		87.9		84.2
Post-radiation sinusitis		0.008		< 0.001		< 0.001		0.003
No	97.4		92.1		97.9		94.1
Yes	84.4		66.5		81.7		79.8

Abbreviations: p p-value, OS overall survival rate, DFS disease-free survival rate, FFLF freedom from local failure, FFDF freedom from distant failure