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Table 1 Patient characteristics

From: Salivary gland carcinoma (SGC) with perineural spread and/or positive resection margin – high locoregional control rates after photon (chemo) radiotherapy - experience from a monocentric analysis

Patients’ characteristics (n = 65)

Characteristics

Value

%

Gender (Number of patients)

 female

30

46.2%

 male

35

53.8%

Age at diagnosis (years)

 Median

57

 

 Range

26–83

 

Primary tumor site (Number of patients)

 Parotid Gland

36

55.4%

 Submandibular Gland

11

16.9%

 Minor Salivary Glands:

18

27.7%

 - Nasal cavity/paranasal sinus

6

 

 - Hard palate

3

 

 - Tongue/base of tongue

5

 

 - Meatus acusticus

2

 

 - Floor of mouth

1

 

 - Cheek

1

 

Histologic Subtypes (Number of patients)

 Adenoidcystic Carcinoma

25

38.5%

 Mucoepidermoid Carcinoma

13

20.0%

 Ductal Adenocarcinoma

19

29.2%

 Adenocarcinoma NOS

4

6.2%

 Acinic cell carcinoma

2

3.1%

 other

2

3.1%

Tumor stage (Number of Patients)

 pT1

9

13.8%

 pT2

10

15.4%

 pT3

30

46.2%

 pT4

16

24.6%

 pT4a

13

 

 pT4b

3

 

Primary tumor size (cm)

 Median:

2.8

 

 Range:

1–8.5

 

Nodal Stage (Number of Patients)

 c/pN0

27

41.5%

 pN1

14

21.5%

 pN2b

24

36.9%

Perinodal Spread (Number of Patients)

 no

39

60.0%

 yes

21

32.3%

 unknown

5

7.7%

Lymphangiosis (Number of patients)

 L0

43

66.2%

 L1

20

30.8%

 Lx

2

3.1%

Hemangiosis (Number of patients)

 V0

52

80.0%

 V1

11

16.9%

 Vx

2

3.1%

Perineural Spread (Number of Patients)

 Pn0

6

9.2%

 Pn1

59

90.8%

Resection margin (Number of Patients)

 R0

40

61.5%

 R1

19

29.2%

 R2

6

9.2%

Grade of Differentiation (Number of Patients)

 Low-grade

6

9.2%

 Intermediate-grade

11

16.9%

 High-grade

47

72.3%

 Gx

1

1.5%

Bone Infiltration of primary tumor

 No

59

90.8%

 Yes

6

9.2%

Neck Dissection (Number of Patients)

 None

10

15.4%

 Ipsilateral

48

73.8%

 Bilateral

7

10.8%

Radio (chemo) therapy (Number of patients)

 Radiation alone

24

36.9%

 Radiochemotherapy

41

63.1%

Radiation dose (Gy):

 Median: 64

  

 Range: 45–74.2Gy

  

Radiation technique (Number of patients)

 3D:

38

58.5%

 IMRT:

27

41.5%

Planning target volume (number of patients)

 Primary tumor region

11

16.9%

 Primary tumor region, ipsilateral neck

35

53.8%

 Primary tumor region, bilateral neck

19

29.2%