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Table 1 Patient characteristics

From: Salivary gland carcinoma (SGC) with perineural spread and/or positive resection margin – high locoregional control rates after photon (chemo) radiotherapy - experience from a monocentric analysis

Patients’ characteristics (n = 65)
Characteristics Value %
Gender (Number of patients)
 female 30 46.2%
 male 35 53.8%
Age at diagnosis (years)
 Median 57  
 Range 26–83  
Primary tumor site (Number of patients)
 Parotid Gland 36 55.4%
 Submandibular Gland 11 16.9%
 Minor Salivary Glands: 18 27.7%
 - Nasal cavity/paranasal sinus 6  
 - Hard palate 3  
 - Tongue/base of tongue 5  
 - Meatus acusticus 2  
 - Floor of mouth 1  
 - Cheek 1  
Histologic Subtypes (Number of patients)
 Adenoidcystic Carcinoma 25 38.5%
 Mucoepidermoid Carcinoma 13 20.0%
 Ductal Adenocarcinoma 19 29.2%
 Adenocarcinoma NOS 4 6.2%
 Acinic cell carcinoma 2 3.1%
 other 2 3.1%
Tumor stage (Number of Patients)
 pT1 9 13.8%
 pT2 10 15.4%
 pT3 30 46.2%
 pT4 16 24.6%
 pT4a 13  
 pT4b 3  
Primary tumor size (cm)
 Median: 2.8  
 Range: 1–8.5  
Nodal Stage (Number of Patients)
 c/pN0 27 41.5%
 pN1 14 21.5%
 pN2b 24 36.9%
Perinodal Spread (Number of Patients)
 no 39 60.0%
 yes 21 32.3%
 unknown 5 7.7%
Lymphangiosis (Number of patients)
 L0 43 66.2%
 L1 20 30.8%
 Lx 2 3.1%
Hemangiosis (Number of patients)
 V0 52 80.0%
 V1 11 16.9%
 Vx 2 3.1%
Perineural Spread (Number of Patients)
 Pn0 6 9.2%
 Pn1 59 90.8%
Resection margin (Number of Patients)
 R0 40 61.5%
 R1 19 29.2%
 R2 6 9.2%
Grade of Differentiation (Number of Patients)
 Low-grade 6 9.2%
 Intermediate-grade 11 16.9%
 High-grade 47 72.3%
 Gx 1 1.5%
Bone Infiltration of primary tumor
 No 59 90.8%
 Yes 6 9.2%
Neck Dissection (Number of Patients)
 None 10 15.4%
 Ipsilateral 48 73.8%
 Bilateral 7 10.8%
Radio (chemo) therapy (Number of patients)
 Radiation alone 24 36.9%
 Radiochemotherapy 41 63.1%
Radiation dose (Gy):
 Median: 64   
 Range: 45–74.2Gy   
Radiation technique (Number of patients)
 3D: 38 58.5%
 IMRT: 27 41.5%
Planning target volume (number of patients)
 Primary tumor region 11 16.9%
 Primary tumor region, ipsilateral neck 35 53.8%
 Primary tumor region, bilateral neck 19 29.2%